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P80750 (RIPX_CUCPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 31, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosome-inactivating protein

EC=3.2.2.22
Alternative name(s):
rRNA N-glycosidase
OrganismCucurbita pepo (Vegetable marrow) (Summer squash)
Taxonomic identifier3663 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidsfabidsCucurbitalesCucurbitaceaeCucurbiteaeCucurbita

Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.

Sequence similarities

Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.

Ontologies

Keywords
   Biological processPlant defense
   Molecular functionHydrolase
Protein synthesis inhibitor
Toxin
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

negative regulation of translation

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionrRNA N-glycosylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›20›20Ribosome-inactivating protein
PRO_0000221399

Experimental info

Non-terminal residue201

Sequences

Sequence LengthMass (Da)Tools
P80750 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 8E753D217FDEAA6D

FASTA202,235
        10         20 
NVRFDLSGAT SSSYKTFIKN 

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References

[1]"Purification, characterization and subcellular localization of a type-1 ribosome-inactivating protein from the sarcocarp of Cucurbita pepo."
Yoshinari S., Yokota S., Sawmoto H., Koresawa S., Tamura M., Endo Y.
Eur. J. Biochem. 242:585-591(1996) [PubMed: 9022685] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Mesocarp.

Cross-references

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

PROSITEPS00275. SHIGA_RICIN. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRIPX_CUCPE
AccessionPrimary (citable) accession number: P80750
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 31, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families