Reviewed,
UniProtKB/Swiss-Prot P80750 (RIPX_CUCPE)
Last modified
February 9, 2010.
Version 40.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Ribosome-inactivating protein EC=3.2.2.22 Alternative name(s): rRNA N-glycosidase |
| Organism | Cucurbita pepo (Vegetable marrow) (Summer squash) |
| Taxonomic identifier | 3663 [NCBI] |
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Cucurbitales › Cucurbitaceae › Cucurbita |
Protein attributes
| Sequence length | 20 AA. |
| Sequence status | Fragment. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA. |
| Sequence similarities | Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Plant defense |
| Molecular function | Hydrolase Protein synthesis inhibitor Toxin |
| Technical term | Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | defense response Inferred from electronic annotation. Source: UniProtKB-KW negative regulation of translationInferred from electronic annotation. Source: UniProtKB-KW pathogenesisInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | rRNA N-glycosylase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "Purification, characterization and subcellular localization of a type-1 ribosome-inactivating protein from the sarcocarp of Cucurbita pepo." Yoshinari S., Yokota S., Sawmoto H., Koresawa S., Tamura M., Endo Y. Eur. J. Biochem. 242:585-591(1996) [PubMed: 9022685] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Mesocarp. |
Cross-references
3D structure databases | |
|---|---|
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 3.2.2.22. 1943. |
Family and domain databases | |
| PROSITE | PS00275. SHIGA_RICIN. Partial match. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RIPX_CUCPE | ||||||||
| Accession | Primary (citable) accession number: P80750 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||

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