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Protein

Major pollen allergen Ole e 4

Gene
N/A
Organism
Olea europaea (Common olive)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Ole e 4
Alternative name(s):
Allergen Ole e IV
Allergen: Ole e 4
OrganismiOlea europaea (Common olive)
Taxonomic identifieri4146 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesOleaceaeOleeaeOlea

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Major allergen from olive pollen. Important in Mediterranean countries.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3385. Ole e 4.0101.
492. Ole e 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›24›24Major pollen allergen Ole e 4PRO_0000064559Add
BLAST

Post-translational modificationi

The N-terminus is blocked.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Sequencei

Sequence statusi: Fragments.

P80741-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
AFANTGVEIV SIDTYLFSLY DEDK
Length:24
Mass (Da):2,711
Last modified:November 1, 1997 - v1
Checksum:iADACE5DA9F577D6D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-adjacent residuesi10 – 112Curated
Non-terminal residuei24 – 241

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3385. Ole e 4.0101.
492. Ole e 4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Purification, characterization, and partial sequencing of two new allergens of Olea europaea."
    Boluda L., Alonso C., Fernandez-Caldas E.
    J. Allergy Clin. Immunol. 101:210-216(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Tissue: Pollen.
  2. Cited for: REVIEW, NOMENCLATURE.

Entry informationi

Entry nameiALL4_OLEEU
AccessioniPrimary (citable) accession number: P80741
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 1, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

The sequences determined for the two internal peptides of Ole e 4 are identical to internal fragments of Ole e 9. However, the apparent molecular weight of the two proteins is different and they are still classified as two separate allergens (PubMed:22385802), even though we may be facing two different isoforms of the same allergen.1 Publication

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.