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P80731 (NUO8_SOLTU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADH-ubiquinone oxidoreductase 12 kDa subunit

EC=1.6.5.3
EC=1.6.99.3
Alternative name(s):
Complex I-12kD
Short name=CI-12kD
OrganismSolanum tuberosum (Potato) [Reference proteome]
Taxonomic identifier4113 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Protein attributes

Sequence length15 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Catalytic activity

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).

NADH + acceptor = NAD+ + reduced acceptor.

Subunit structure

Complex I is composed of about 45 different subunits By similarity.

Subcellular location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   LigandNAD
Ubiquinone
   Molecular functionOxidoreductase
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componentmitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›15›15NADH-ubiquinone oxidoreductase 12 kDa subunit
PRO_0000118855

Experimental info

Non-terminal residue151

Sequences

Sequence LengthMass (Da)Tools
P80731 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: EDC87B30AD155854

FASTA151,672
        10 
VHMARNMXVP PXXAD 

« Hide

References

[1]Herz U., Grohmann L.
Submitted (DEC-1996) to UniProtKB
Cited for: PROTEIN SEQUENCE.
Strain: cv. Bintje.
Tissue: Tuber.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameNUO8_SOLTU
AccessionPrimary (citable) accession number: P80731
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program