Reviewed, UniProtKB/Swiss-Prot P80683 (CUA3A_TENMO)

Names and origin

Protein names	Recommended name:     Larval cuticle protein A3A Alternative name(s):     TM-LCP A3A       Short name=TM-A3A
Organism	Tenebrio molitor (Yellow mealworm)
Taxonomic identifier	7067 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Coleoptera › Polyphaga › Cucujiformia › Tenebrionidae › Tenebrio

Protein attributes

Sequence length	134 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of the larva of Tenebrio molitor.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Sequence similarities	Contains 1 chitin-binding type R&R domain.
Mass spectrometry	Molecular weight is 13974.3 Da from positions 1 - 134. Determined by ESI. Ref.1

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 134	134	Larval cuticle protein A3A		PRO_0000196134
Regions
	Repeat	23 – 26	4	1
	Domain	40 – 106	67	Chitin-binding type R&R
	Repeat	111 – 114	4	2

Sequences

	Sequence		Length	Mass (Da)
	P80683-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: F6AAAF06444FE93E	FASTA	134	13,976
	10 20 30 40 50 60 GLIGAPIAAP LGYAAPFARA AVAAPVAVAK TVVADEYDPH PQYSYGYDIQ DGLTGDSKNQ 70 80 90 100 110 120 QETRDGDVVQ GSYSLVDPDG TRRTVEYTAD PINGFNAVVH REPLVAKAVV AAPAIAKVHA 130 PLAYGAPVAK YAFH

References

[1]	"Sequence studies of proteins from larval and pupal cuticle of the yellow meal worm, Tenebrio molitor." Andersen S.O., Rafn K., Roepstorff P. Insect Biochem. Mol. Biol. 27:121-131(1997) [PubMed: 9066122] [Abstract] Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY. Tissue: Cuticle.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR000618. Insect_cuticle. [Graphical view]
Pfam	PF00379. Chitin_bind_4. 1 hit. [Graphical view]
PRINTS	PR00947. CUTICLE.
PROSITE	PS00233. CHIT_BIND_RR_1. 1 hit. PS51155. CHIT_BIND_RR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CUA3A_TENMO

Accession

Primary (citable) accession number: P80683

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 25, 2008
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)