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Protein

Larval cuticle protein A1A

Gene
N/A
Organism
Tenebrio molitor (Yellow mealworm beetle)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Component of the cuticle of the larva of Tenebrio molitor.

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Larval cuticle protein A1A
Alternative name(s):
TM-LCP A1A
Short name:
TM-A1A
OrganismiTenebrio molitor (Yellow mealworm beetle)
Taxonomic identifieri7067 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrio

Subcellular locationi

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 174174Larval cuticle protein A1APRO_0000196132Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati45 – 4841
Repeati67 – 7042
Domaini84 – 15067Chitin-binding type R&RPROSITE-ProRule annotationAdd
BLAST
Repeati155 – 15843

Domaini

The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.

Sequence similaritiesi

Contains 1 chitin-binding type R&R domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

InterProiIPR000618. Insect_cuticle.
[Graphical view]
PfamiPF00379. Chitin_bind_4. 1 hit.
[Graphical view]
PRINTSiPR00947. CUTICLE.
PROSITEiPS00233. CHIT_BIND_RR_1. 1 hit.
PS51155. CHIT_BIND_RR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P80681-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GLVGAPATLS TAPIAYGGYG GYGAYGGSLL RAAPIARVAS PLAYAAPVAR
60 70 80 90 100
VAAPLAYAAP YARAAVAAPV AVAKTVVADE YDPNPQYSFG YDVQDGLTGD
110 120 130 140 150
SKNQVESRSG DVVQGSYSLV DPDGTRRTVE YTADPINGFN AVVHREPLVA
160 170
KAVVAAPAIA KVHAPLAYSG GYLH
Length:174
Mass (Da):17,692
Last modified:October 1, 1996 - v1
Checksum:i29BB3E508604AE1A
GO

Mass spectrometryi

Molecular mass is 17692.5 Da from positions 1 - 174. Determined by ESI. 1 Publication

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000618. Insect_cuticle.
[Graphical view]
PfamiPF00379. Chitin_bind_4. 1 hit.
[Graphical view]
PRINTSiPR00947. CUTICLE.
PROSITEiPS00233. CHIT_BIND_RR_1. 1 hit.
PS51155. CHIT_BIND_RR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence studies of proteins from larval and pupal cuticle of the yellow meal worm, Tenebrio molitor."
    Andersen S.O., Rafn K., Roepstorff P.
    Insect Biochem. Mol. Biol. 27:121-131(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, MASS SPECTROMETRY.
    Tissue: Cuticle.

Entry informationi

Entry nameiCUA1A_TENMO
AccessioniPrimary (citable) accession number: P80681
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.