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P80564

- PGTS_PELAC

UniProt

P80564 - PGTS_PELAC

Protein

Pyrogallol hydroxytransferase small subunit

Gene

bthL

Organism
Pelobacter acidigallici
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 2 (16 Jan 2004)
      Previous versions | rss
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    Functioni

    Isomerization of pyrogallol to phloroglucin.

    Catalytic activityi

    1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.

    Cofactori

    Binds 3 4Fe-4S clusters.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi13 – 131Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi16 – 161Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi19 – 191Iron-sulfur 1 (4Fe-4S)By similarity
    Metal bindingi23 – 231Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi68 – 681Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi71 – 711Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi76 – 761Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi109 – 1091Iron-sulfur 3 (4Fe-4S)By similarity
    Metal bindingi126 – 1261Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi129 – 1291Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi145 – 1451Iron-sulfur 2 (4Fe-4S)By similarity
    Metal bindingi149 – 1491Iron-sulfur 1 (4Fe-4S)By similarity

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. pyrogallol hydroxytransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Protein family/group databases

    TCDBi5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyrogallol hydroxytransferase small subunit (EC:1.97.1.2)
    Alternative name(s):
    Transhydroxylase subunit beta
    Gene namesi
    Name:bthL
    OrganismiPelobacter acidigallici
    Taxonomic identifieri35816 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 274274Pyrogallol hydroxytransferase small subunitPRO_0000058366Add
    BLAST

    Interactioni

    Subunit structurei

    Heterodimer of a large and a small subunit.

    Structurei

    Secondary structure

    1
    274
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi3 – 97
    Helixi10 – 123
    Helixi18 – 2710
    Turni33 – 353
    Beta strandi45 – 5410
    Beta strandi60 – 667
    Helixi75 – 795
    Turni80 – 823
    Beta strandi83 – 864
    Beta strandi92 – 943
    Turni96 – 1016
    Helixi103 – 1086
    Beta strandi115 – 1173
    Turni118 – 1214
    Beta strandi122 – 1243
    Helixi130 – 1334
    Helixi144 – 1485
    Beta strandi154 – 1596
    Helixi161 – 17111
    Helixi178 – 1803
    Beta strandi185 – 1906
    Helixi192 – 1954
    Beta strandi197 – 2059
    Beta strandi214 – 2196
    Beta strandi222 – 2287
    Beta strandi233 – 2408
    Beta strandi242 – 25110
    Beta strandi254 – 26512
    Beta strandi267 – 2748

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1TI2X-ray2.35B/D/F/H/J/L1-274[»]
    1TI4X-ray2.20B/D/F/H/J/L1-274[»]
    1TI6X-ray2.00B/D/F/H/J/L1-274[»]
    1VLDX-ray2.35N/P/R/T/V/X1-274[»]
    1VLEX-ray2.20N/P/R/T/V/X1-274[»]
    1VLFX-ray2.00N/P/R/T/V/X1-274[»]
    ProteinModelPortaliP80564.
    SMRiP80564. Positions 1-274.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP80564.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR017896. 4Fe4S_Fe-S-bd.
    IPR008454. Collagen-bd_Cna-like_B-typ_dom.
    IPR008970. Collagen-bd_Cna_B-typ_dom.
    IPR013783. Ig-like_fold.
    [Graphical view]
    PfamiPF05738. Cna_B. 1 hit.
    PF13247. Fer4_11. 1 hit.
    [Graphical view]
    SUPFAMiSSF49478. SSF49478. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P80564-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEQYYMVIDV AKCQDCNNCF MGCMDEHELN EWPGYTASMQ RGHRWMNIER    50
    RERGTYPRND INYRPTPCMH CENAPCVAKG NGAVYQREDG IVLIDPEKAK 100
    GKKELLDTCP YGVMYWNEEE NVAQKCTMCA HLLDDESWAP KMPRCAHNCG 150
    SFVYEFLKTT PEAMAKKVEE EGLEVIKPEL GTKPRVYYKN LYRFEKNYVT 200
    AGILVQGDCF EGAKVVLKSG GKEVASAETN FFGEFKFDAL DNGEYTVEID 250
    ADGKSYSDTV VIDDKSVDLG FIKL 274
    Length:274
    Mass (Da):31,221
    Last modified:January 16, 2004 - v2
    Checksum:i2F9A9CD24082F5A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ243850 Genomic DNA. Translation: CAB50914.1.
    PIRiS65429.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ243850 Genomic DNA. Translation: CAB50914.1 .
    PIRi S65429.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1TI2 X-ray 2.35 B/D/F/H/J/L 1-274 [» ]
    1TI4 X-ray 2.20 B/D/F/H/J/L 1-274 [» ]
    1TI6 X-ray 2.00 B/D/F/H/J/L 1-274 [» ]
    1VLD X-ray 2.35 N/P/R/T/V/X 1-274 [» ]
    1VLE X-ray 2.20 N/P/R/T/V/X 1-274 [» ]
    1VLF X-ray 2.00 N/P/R/T/V/X 1-274 [» ]
    ProteinModelPortali P80564.
    SMRi P80564. Positions 1-274.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P80564.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR017896. 4Fe4S_Fe-S-bd.
    IPR008454. Collagen-bd_Cna-like_B-typ_dom.
    IPR008970. Collagen-bd_Cna_B-typ_dom.
    IPR013783. Ig-like_fold.
    [Graphical view ]
    Pfami PF05738. Cna_B. 1 hit.
    PF13247. Fer4_11. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49478. SSF49478. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Retey J.
      Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "One molecule of molybdopterin guanine dinucleotide is associated with each subunit of the heterodimeric Mo-Fe-S protein transhydroxylase of Pelobacter acidigallici as determined by SDS/PAGE and mass spectrometry."
      Reichenbecher W., Ruediger A., Kroneck P.M.H., Schink B.
      Eur. J. Biochem. 237:406-413(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-15.
      Strain: DSM 2377 / Braunschweig.
    3. "Towards the reaction mechanism of pyrogallol-phloroglucinol transhydroxylase of Pelobacter acidigallici."
      Reichenbecher W., Schink B.
      Biochim. Biophys. Acta 1430:245-253(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.

    Entry informationi

    Entry nameiPGTS_PELAC
    AccessioniPrimary (citable) accession number: P80564
    Secondary accession number(s): Q9XAY5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: January 16, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3