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P80564 (PGTS_PELAC) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyrogallol hydroxytransferase small subunit

EC=1.97.1.2
Alternative name(s):
Transhydroxylase subunit beta
Gene names
Name:bthL
OrganismPelobacter acidigallici
Taxonomic identifier35816 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Isomerization of pyrogallol to phloroglucin.

Catalytic activity

1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.

Cofactor

Binds 3 4Fe-4S clusters.

Subunit structure

Heterodimer of a large and a small subunit.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Pyrogallol hydroxytransferase small subunit
PRO_0000058366

Sites

Metal binding131Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding161Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding191Iron-sulfur 1 (4Fe-4S) By similarity
Metal binding231Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding681Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding711Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding761Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding1091Iron-sulfur 3 (4Fe-4S) By similarity
Metal binding1261Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1291Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1451Iron-sulfur 2 (4Fe-4S) By similarity
Metal binding1491Iron-sulfur 1 (4Fe-4S) By similarity

Secondary structure

..................................................... 274
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P80564 [UniParc].

Last modified January 16, 2004. Version 2.
Checksum: 2F9A9CD24082F5A1

FASTA27431,221
        10         20         30         40         50         60 
MEQYYMVIDV AKCQDCNNCF MGCMDEHELN EWPGYTASMQ RGHRWMNIER RERGTYPRND 

        70         80         90        100        110        120 
INYRPTPCMH CENAPCVAKG NGAVYQREDG IVLIDPEKAK GKKELLDTCP YGVMYWNEEE 

       130        140        150        160        170        180 
NVAQKCTMCA HLLDDESWAP KMPRCAHNCG SFVYEFLKTT PEAMAKKVEE EGLEVIKPEL 

       190        200        210        220        230        240 
GTKPRVYYKN LYRFEKNYVT AGILVQGDCF EGAKVVLKSG GKEVASAETN FFGEFKFDAL 

       250        260        270 
DNGEYTVEID ADGKSYSDTV VIDDKSVDLG FIKL 

« Hide

References

[1]Retey J.
Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"One molecule of molybdopterin guanine dinucleotide is associated with each subunit of the heterodimeric Mo-Fe-S protein transhydroxylase of Pelobacter acidigallici as determined by SDS/PAGE and mass spectrometry."
Reichenbecher W., Ruediger A., Kroneck P.M.H., Schink B.
Eur. J. Biochem. 237:406-413(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-15.
Strain: DSM 2377 / Braunschweig.
[3]"Towards the reaction mechanism of pyrogallol-phloroglucinol transhydroxylase of Pelobacter acidigallici."
Reichenbecher W., Schink B.
Biochim. Biophys. Acta 1430:245-253(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ243850 Genomic DNA. Translation: CAB50914.1.
PIRS65429.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1TI2X-ray2.35B/D/F/H/J/L1-274[»]
1TI4X-ray2.20B/D/F/H/J/L1-274[»]
1TI6X-ray2.00B/D/F/H/J/L1-274[»]
1VLDX-ray2.35N/P/R/T/V/X1-274[»]
1VLEX-ray2.20N/P/R/T/V/X1-274[»]
1VLFX-ray2.00N/P/R/T/V/X1-274[»]
ProteinModelPortalP80564.
SMRP80564. Positions 1-274.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

TCDB5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR017896. 4Fe4S_Fe-S-bd.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR008970. Collagen-bd_Cna_B-typ_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamPF05738. Cna_B. 1 hit.
PF13247. Fer4_11. 1 hit.
[Graphical view]
SUPFAMSSF49478. SSF49478. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP80564.

Entry information

Entry namePGTS_PELAC
AccessionPrimary (citable) accession number: P80564
Secondary accession number(s): Q9XAY5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 16, 2004
Last modified: October 16, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references