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P80564

- PGTS_PELAC

UniProt

P80564 - PGTS_PELAC

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Protein
Pyrogallol hydroxytransferase small subunit
Gene
bthL
Organism
Pelobacter acidigallici
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Isomerization of pyrogallol to phloroglucin.

Catalytic activityi

1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.

Cofactori

Binds 3 4Fe-4S clusters.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi13 – 131Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi16 – 161Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi19 – 191Iron-sulfur 1 (4Fe-4S) By similarity
Metal bindingi23 – 231Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi68 – 681Iron-sulfur 3 (4Fe-4S) By similarity
Metal bindingi71 – 711Iron-sulfur 3 (4Fe-4S) By similarity
Metal bindingi76 – 761Iron-sulfur 3 (4Fe-4S) By similarity
Metal bindingi109 – 1091Iron-sulfur 3 (4Fe-4S) By similarity
Metal bindingi126 – 1261Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi129 – 1291Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi145 – 1451Iron-sulfur 2 (4Fe-4S) By similarity
Metal bindingi149 – 1491Iron-sulfur 1 (4Fe-4S) By similarity

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. pyrogallol hydroxytransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Protein family/group databases

TCDBi5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrogallol hydroxytransferase small subunit (EC:1.97.1.2)
Alternative name(s):
Transhydroxylase subunit beta
Gene namesi
Name:bthL
OrganismiPelobacter acidigallici
Taxonomic identifieri35816 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 274274Pyrogallol hydroxytransferase small subunit
PRO_0000058366Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large and a small subunit.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 97
Helixi10 – 123
Helixi18 – 2710
Turni33 – 353
Beta strandi45 – 5410
Beta strandi60 – 667
Helixi75 – 795
Turni80 – 823
Beta strandi83 – 864
Beta strandi92 – 943
Turni96 – 1016
Helixi103 – 1086
Beta strandi115 – 1173
Turni118 – 1214
Beta strandi122 – 1243
Helixi130 – 1334
Helixi144 – 1485
Beta strandi154 – 1596
Helixi161 – 17111
Helixi178 – 1803
Beta strandi185 – 1906
Helixi192 – 1954
Beta strandi197 – 2059
Beta strandi214 – 2196
Beta strandi222 – 2287
Beta strandi233 – 2408
Beta strandi242 – 25110
Beta strandi254 – 26512
Beta strandi267 – 2748

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TI2X-ray2.35B/D/F/H/J/L1-274[»]
1TI4X-ray2.20B/D/F/H/J/L1-274[»]
1TI6X-ray2.00B/D/F/H/J/L1-274[»]
1VLDX-ray2.35N/P/R/T/V/X1-274[»]
1VLEX-ray2.20N/P/R/T/V/X1-274[»]
1VLFX-ray2.00N/P/R/T/V/X1-274[»]
ProteinModelPortaliP80564.
SMRiP80564. Positions 1-274.

Miscellaneous databases

EvolutionaryTraceiP80564.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR008970. Collagen-bd_Cna_B-typ_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF05738. Cna_B. 1 hit.
PF13247. Fer4_11. 1 hit.
[Graphical view]
SUPFAMiSSF49478. SSF49478. 1 hit.

Sequencei

Sequence statusi: Complete.

P80564-1 [UniParc]FASTAAdd to Basket

« Hide

MEQYYMVIDV AKCQDCNNCF MGCMDEHELN EWPGYTASMQ RGHRWMNIER    50
RERGTYPRND INYRPTPCMH CENAPCVAKG NGAVYQREDG IVLIDPEKAK 100
GKKELLDTCP YGVMYWNEEE NVAQKCTMCA HLLDDESWAP KMPRCAHNCG 150
SFVYEFLKTT PEAMAKKVEE EGLEVIKPEL GTKPRVYYKN LYRFEKNYVT 200
AGILVQGDCF EGAKVVLKSG GKEVASAETN FFGEFKFDAL DNGEYTVEID 250
ADGKSYSDTV VIDDKSVDLG FIKL 274
Length:274
Mass (Da):31,221
Last modified:January 16, 2004 - v2
Checksum:i2F9A9CD24082F5A1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243850 Genomic DNA. Translation: CAB50914.1.
PIRiS65429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243850 Genomic DNA. Translation: CAB50914.1 .
PIRi S65429.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1TI2 X-ray 2.35 B/D/F/H/J/L 1-274 [» ]
1TI4 X-ray 2.20 B/D/F/H/J/L 1-274 [» ]
1TI6 X-ray 2.00 B/D/F/H/J/L 1-274 [» ]
1VLD X-ray 2.35 N/P/R/T/V/X 1-274 [» ]
1VLE X-ray 2.20 N/P/R/T/V/X 1-274 [» ]
1VLF X-ray 2.00 N/P/R/T/V/X 1-274 [» ]
ProteinModelPortali P80564.
SMRi P80564. Positions 1-274.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P80564.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR017896. 4Fe4S_Fe-S-bd.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR008970. Collagen-bd_Cna_B-typ_dom.
IPR013783. Ig-like_fold.
[Graphical view ]
Pfami PF05738. Cna_B. 1 hit.
PF13247. Fer4_11. 1 hit.
[Graphical view ]
SUPFAMi SSF49478. SSF49478. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Retey J.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "One molecule of molybdopterin guanine dinucleotide is associated with each subunit of the heterodimeric Mo-Fe-S protein transhydroxylase of Pelobacter acidigallici as determined by SDS/PAGE and mass spectrometry."
    Reichenbecher W., Ruediger A., Kroneck P.M.H., Schink B.
    Eur. J. Biochem. 237:406-413(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-15.
    Strain: DSM 2377 / Braunschweig.
  3. "Towards the reaction mechanism of pyrogallol-phloroglucinol transhydroxylase of Pelobacter acidigallici."
    Reichenbecher W., Schink B.
    Biochim. Biophys. Acta 1430:245-253(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiPGTS_PELAC
AccessioniPrimary (citable) accession number: P80564
Secondary accession number(s): Q9XAY5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 16, 2004
Last modified: October 16, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3

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