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P80564

- PGTS_PELAC

UniProt

P80564 - PGTS_PELAC

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Protein

Pyrogallol hydroxytransferase small subunit

Gene

bthL

Organism
Pelobacter acidigallici
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Isomerization of pyrogallol to phloroglucin.

Catalytic activityi

1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.

Cofactori

[4Fe-4S] clusterNote: Binds 3 [4Fe-4S] clusters.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi13 – 131Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi16 – 161Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi19 – 191Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi23 – 231Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi68 – 681Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi71 – 711Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi76 – 761Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi109 – 1091Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi126 – 1261Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi129 – 1291Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi145 – 1451Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi149 – 1491Iron-sulfur 1 (4Fe-4S)By similarity

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. pyrogallol hydroxytransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Protein family/group databases

TCDBi5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrogallol hydroxytransferase small subunit (EC:1.97.1.2)
Alternative name(s):
Transhydroxylase subunit beta
Gene namesi
Name:bthL
OrganismiPelobacter acidigallici
Taxonomic identifieri35816 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 274274Pyrogallol hydroxytransferase small subunitPRO_0000058366Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large and a small subunit.

Structurei

Secondary structure

1
274
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 97Combined sources
Helixi10 – 123Combined sources
Helixi18 – 2710Combined sources
Turni33 – 353Combined sources
Beta strandi45 – 5410Combined sources
Beta strandi60 – 667Combined sources
Helixi75 – 795Combined sources
Turni80 – 823Combined sources
Beta strandi83 – 864Combined sources
Beta strandi92 – 943Combined sources
Turni96 – 1016Combined sources
Helixi103 – 1086Combined sources
Beta strandi115 – 1173Combined sources
Turni118 – 1214Combined sources
Beta strandi122 – 1243Combined sources
Helixi130 – 1334Combined sources
Helixi144 – 1485Combined sources
Beta strandi154 – 1596Combined sources
Helixi161 – 17111Combined sources
Helixi178 – 1803Combined sources
Beta strandi185 – 1906Combined sources
Helixi192 – 1954Combined sources
Beta strandi197 – 2059Combined sources
Beta strandi214 – 2196Combined sources
Beta strandi222 – 2287Combined sources
Beta strandi233 – 2408Combined sources
Beta strandi242 – 25110Combined sources
Beta strandi254 – 26512Combined sources
Beta strandi267 – 2748Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TI2X-ray2.35B/D/F/H/J/L1-274[»]
1TI4X-ray2.20B/D/F/H/J/L1-274[»]
1TI6X-ray2.00B/D/F/H/J/L1-274[»]
1VLDX-ray2.35N/P/R/T/V/X1-274[»]
1VLEX-ray2.20N/P/R/T/V/X1-274[»]
1VLFX-ray2.00N/P/R/T/V/X1-274[»]
ProteinModelPortaliP80564.
SMRiP80564. Positions 1-274.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP80564.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR008970. Collagen-bd_Cna_B-typ_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF05738. Cna_B. 1 hit.
PF13247. Fer4_11. 1 hit.
[Graphical view]
SUPFAMiSSF49478. SSF49478. 1 hit.

Sequencei

Sequence statusi: Complete.

P80564-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQYYMVIDV AKCQDCNNCF MGCMDEHELN EWPGYTASMQ RGHRWMNIER
60 70 80 90 100
RERGTYPRND INYRPTPCMH CENAPCVAKG NGAVYQREDG IVLIDPEKAK
110 120 130 140 150
GKKELLDTCP YGVMYWNEEE NVAQKCTMCA HLLDDESWAP KMPRCAHNCG
160 170 180 190 200
SFVYEFLKTT PEAMAKKVEE EGLEVIKPEL GTKPRVYYKN LYRFEKNYVT
210 220 230 240 250
AGILVQGDCF EGAKVVLKSG GKEVASAETN FFGEFKFDAL DNGEYTVEID
260 270
ADGKSYSDTV VIDDKSVDLG FIKL
Length:274
Mass (Da):31,221
Last modified:January 16, 2004 - v2
Checksum:i2F9A9CD24082F5A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243850 Genomic DNA. Translation: CAB50914.1.
PIRiS65429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243850 Genomic DNA. Translation: CAB50914.1 .
PIRi S65429.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1TI2 X-ray 2.35 B/D/F/H/J/L 1-274 [» ]
1TI4 X-ray 2.20 B/D/F/H/J/L 1-274 [» ]
1TI6 X-ray 2.00 B/D/F/H/J/L 1-274 [» ]
1VLD X-ray 2.35 N/P/R/T/V/X 1-274 [» ]
1VLE X-ray 2.20 N/P/R/T/V/X 1-274 [» ]
1VLF X-ray 2.00 N/P/R/T/V/X 1-274 [» ]
ProteinModelPortali P80564.
SMRi P80564. Positions 1-274.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 5.A.3.7.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P80564.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR017896. 4Fe4S_Fe-S-bd.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR008970. Collagen-bd_Cna_B-typ_dom.
IPR013783. Ig-like_fold.
[Graphical view ]
Pfami PF05738. Cna_B. 1 hit.
PF13247. Fer4_11. 1 hit.
[Graphical view ]
SUPFAMi SSF49478. SSF49478. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Retey J.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "One molecule of molybdopterin guanine dinucleotide is associated with each subunit of the heterodimeric Mo-Fe-S protein transhydroxylase of Pelobacter acidigallici as determined by SDS/PAGE and mass spectrometry."
    Reichenbecher W., Ruediger A., Kroneck P.M.H., Schink B.
    Eur. J. Biochem. 237:406-413(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-15.
    Strain: DSM 2377 / Braunschweig.
  3. "Towards the reaction mechanism of pyrogallol-phloroglucinol transhydroxylase of Pelobacter acidigallici."
    Reichenbecher W., Schink B.
    Biochim. Biophys. Acta 1430:245-253(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiPGTS_PELAC
AccessioniPrimary (citable) accession number: P80564
Secondary accession number(s): Q9XAY5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 16, 2004
Last modified: November 26, 2014
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3