Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fatty acid-binding protein

Gene

SCP2

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in the transport of fatty acids. Binds fatty acids and fatty acyl-CoAs including palmitic acid, oleic acid, cis-parinaric acid and palmitoyl-CoA (in vitro).2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Enzyme and pathway databases

BRENDAi2.3.1.154. 1122.

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein
Alternative name(s):
Sterol carrier protein 2
YLSCP2
Gene namesi
Name:SCP2
Ordered Locus Names:YALI0E01298g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome E

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 129128Fatty acid-binding proteinPRO_0000097634Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Interactioni

Subunit structurei

Monomer.2 Publications

Structurei

Secondary structure

1
129
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi9 – 113Combined sources
Helixi12 – 2211Combined sources
Helixi24 – 263Combined sources
Helixi27 – 3711Combined sources
Beta strandi39 – 468Combined sources
Beta strandi52 – 598Combined sources
Turni60 – 623Combined sources
Beta strandi65 – 717Combined sources
Beta strandi77 – 837Combined sources
Helixi84 – 918Combined sources
Helixi97 – 1026Combined sources
Beta strandi105 – 1106Combined sources
Helixi112 – 1187Combined sources
Helixi121 – 1266Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JGXX-ray2.20A/B1-129[»]
ProteinModelPortaliP80547.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 129120SCP2Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi127 – 1293Microbody targeting signal

Sequence similaritiesi

Contains 1 SCP2 domain.Curated

Phylogenomic databases

HOGENOMiHOG000141680.
InParanoidiP80547.
OMAiKAFMTGK.
OrthoDBiEOG092C5FPK.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
InterProiIPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF02036. SCP2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P80547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLKVDGFTS SIIFDVIRDG LNDPSQAKQK AESIKKANAI IVFNLKNKAG
60 70 80 90 100
KTESWYLDLK NDGDVGKGNK SPKGDADIQL TLSDDHFQQL VEGKANAQRL
110 120
FMTGKLKVKG NVMKAAAIEG ILKNAQNNL
Length:129
Mass (Da):14,034
Last modified:January 23, 2007 - v4
Checksum:i7DCAC98D27D31E89
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti75 – 751D → N AA sequence (PubMed:8828794).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431362 mRNA. Translation: CAD24067.2.
CR382131 Genomic DNA. Translation: CAG78989.1.
RefSeqiXP_503410.1. XM_503410.1.

Genome annotation databases

EnsemblFungiiCAG78989; CAG78989; YALI0_E01298g.
GeneIDi2911748.
KEGGiyli:YALI0E01298g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431362 mRNA. Translation: CAD24067.2.
CR382131 Genomic DNA. Translation: CAG78989.1.
RefSeqiXP_503410.1. XM_503410.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JGXX-ray2.20A/B1-129[»]
ProteinModelPortaliP80547.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG78989; CAG78989; YALI0_E01298g.
GeneIDi2911748.
KEGGiyli:YALI0E01298g.

Phylogenomic databases

HOGENOMiHOG000141680.
InParanoidiP80547.
OMAiKAFMTGK.
OrthoDBiEOG092C5FPK.

Enzyme and pathway databases

BRENDAi2.3.1.154. 1122.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
InterProiIPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF02036. SCP2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSCP2_YARLI
AccessioniPrimary (citable) accession number: P80547
Secondary accession number(s): Q6C7F2, Q8J0I7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 78 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Expressed essentially in cells grown on palmitic acid with small amounts found in cells grown on glucose.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.