Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot P80521 (PORA_METBF)

Last modified November 25, 2008. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesRecommended name:
    Pyruvate synthase subunit porA
    EC=1.2.7.1
Alternative name(s):
    Pyruvate oxidoreductase alpha chain
      Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit alpha
Gene names
Name: porA
Ordered Locus Names: Mbar_A1000
OrganismMethanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]
Taxonomic identifier269797 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).

Subunit structure

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Miscellaneous

It also catalyzes the oxidation of 2-oxobutyrate.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Pyruvate synthase subunit porA
PRO_0000097125

Sequences

Sequence LengthMass (Da)Tools
P80521-1 [UniParc].

Last modified January 10, 2006. Version 2.
Checksum: D7DA8CA3AF2143B6

FASTA40244,503
        10         20         30         40         50         60 
MIDPAYRKKM VVVEGSYAVA HSAKVCRPNV ISAYPITPQT HIVEHLSQFM ADGEIPNCEY 

        70         80         90        100        110        120 
VNVEAEFSAI SALIGASAVG ARTYSATTSQ GLLLMHEALF NTSGMRLPVV MTVANRAVSA 

       130        140        150        160        170        180 
PINIWNDHQD AIAQRDTGWM QLYVEDVQEA CDTLPQLYKI AEDNEIMVPG MVCMDGFILS 

       190        200        210        220        230        240 
HVYEPVVLLE QDLTDNFLPP FQPEDILDPE DPKTFGAFAS PDTYEEFRYL HEQAMQKALP 

       250        260        270        280        290        300 
KIEATAKEFE EVYGRYHGGL IDGYMLDDAE IVVMAMGSIL GTVKDVVDKY RAKGEKIGVL 

       310        320        330        340        350        360 
KVRSFRPFPK EQICKAVKNA HAVVVLDKNI SIGTNEGALF TETKSCLYNS KVRVPVIGYT 

       370        380        390        400 
IGHGGRDIPV ESIAKVIEET KKVAKSGITI ESQFMDLKEE LL 

« Hide

References

« Hide 'large scale' references
[1]"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
J. Bacteriol. 188:7922-7931(2006) [PubMed: 16980466] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Catalytic properties, molecular composition and sequence alignments of pyruvate: ferredoxin oxidoreductase from the methanogenic archaeon Methanosarcina barkeri (strain Fusaro)."
Bock A.-K., Kunow J., Glasemacher J., Schoenheit P.
Eur. J. Biochem. 237:35-44(1996) [PubMed: 8620891] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-38.

Cross-references

Sequence databases

CP000099 Genomic DNA. Translation: AAZ69968.1.
PIRS65416.
RefSeqYP_304548.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3626883.
GenomeReviewsGene locus Mbar_A1000 in contig CP000099_GR.
KEGGmba:Mbar_A1000.
NMPDRfig|269797.3.peg.1011.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP80521.

Enzyme and pathway databases

BioCycMBAR269797:MBAR_A1000-MON.

Family and domain databases

InterProIPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N.
IPR015941. Transketolase_C-like.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
PfamPF01855. POR_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePORA_METBF
AccessionPrimary (citable) accession number: P80521
Secondary accession number(s): Q46DS4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 10, 2006
Last modified: November 25, 2008
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information