P80472 (DHAB_AMYME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Aldehyde dehydrogenase beta chain Short name=ALDH EC=1.2.99.3
Organism	Amycolatopsis methanolica
Taxonomic identifier	1814 [NCBI]
Taxonomic lineage	Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Amycolatopsis

Protein attributes

Sequence length	26 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	An aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.
Cofactor	Molybdenum.
Subunit structure	Heterotrimer composed of an alpha, a beta and a gamma chain.

Ontologies

Keywords
Ligand	Molybdenum
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	UDP-N-acetylmuramate dehydrogenase activity Inferred from electronic annotation. Source: InterPro aldehyde dehydrogenase (pyrroloquinoline-quinone) activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›26	›26	Aldehyde dehydrogenase beta chain		PRO_0000063245
Experimental info
	Non-terminal residue	26	1

Sequences

	Sequence		Length	Mass (Da)
	P80472 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 209C75D48FA7B35C	FASTA	26	2,834
	10 20 MIPAQFTYRR VSSVDEALAA VAEHGD

References

[1]	"A second molybdoprotein aldehyde dehydrogenase from Amycolatopsis methanolica NCIB 11946." Kim S.W., Luykx D.M.A.M., de Vries S., Duine J.A. Arch. Biochem. Biophys. 325:1-7(1996) [PubMed: 8554333] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: DSM 44096 / JCM 8087 / NBRC 15065 / NCIMB 11946.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR016167. FAD-bd_2_sub1. [Graphical view]
Gene3D	G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DHAB_AMYME

Accession

Primary (citable) accession number: P80472

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	October 19, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program