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Protein

10 kDa chaperonin

Gene

groS

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-649-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperonin
Alternative name(s):
10 kDa heat shock protein
GroES protein
HSP10
Protein Cpn10
Gene namesi
Name:groS
Synonyms:groES
Ordered Locus Names:RT0618
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000000604 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 959410 kDa chaperoninPRO_0000174832Add
BLAST

Expressioni

Inductioni

By heat shock.

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.By similarity

Protein-protein interaction databases

STRINGi257363.RT0618.

Structurei

3D structure databases

ProteinModelPortaliP80469.
SMRiP80469. Positions 1-94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.Curated

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
HOGENOMiHOG000133897.
KOiK04078.
OMAiEEYYLFR.
OrthoDBiEOG6GFGSD.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P80469-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFKPLHDRI AIKPIENEEK TKGGIIIPDT AKEKPMQGEI VAVGNGVLNK
60 70 80 90
NGEIYPLELK VGDKVLYGKW AGTEIEIKGE KLIVMKESDV FGIIN
Length:95
Mass (Da):10,476
Last modified:January 23, 2007 - v2
Checksum:i02D92AB59FB91349
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF462073 Genomic DNA. Translation: AAL67575.1.
AE017197 Genomic DNA. Translation: AAU04082.1.
RefSeqiWP_011191062.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04082; AAU04082; RT0618.
KEGGirty:RT0618.
PATRICi17910476. VBIRicTyp34752_0638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF462073 Genomic DNA. Translation: AAL67575.1.
AE017197 Genomic DNA. Translation: AAU04082.1.
RefSeqiWP_011191062.1. NC_006142.1.

3D structure databases

ProteinModelPortaliP80469.
SMRiP80469. Positions 1-94.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi257363.RT0618.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU04082; AAU04082; RT0618.
KEGGirty:RT0618.
PATRICi17910476. VBIRicTyp34752_0638.

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
HOGENOMiHOG000133897.
KOiK04078.
OMAiEEYYLFR.
OrthoDBiEOG6GFGSD.

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-649-MONOMER.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic characterization of groESL operon of Rickettsia typhi (Ethiopian)."
    Radulovic S., Rahman M.S., Beier M.S., Azad A.F.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Ethiopian AZ322.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.
  3. Wu Y., Dasch G.A., Ching W.-M.
    Submitted (FEB-1995) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 2-95.
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiCH10_RICTY
AccessioniPrimary (citable) accession number: P80469
Secondary accession number(s): Q8VQ18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: February 17, 2016
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.