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P80441 (COX3_RHIST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Encoded onMitochondrion
OrganismRhizopus stolonifer (Rhizopus nigricans)
Taxonomic identifier4846 [NCBI]
Taxonomic lineageEukaryotaFungiFungi incertae sedisEarly diverging fungal lineagesMucoromycotinaMucoralesMucorineaeRhizopodaceaeRhizopus

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 281281Cytochrome c oxidase subunit 3
PRO_0000183846

Regions

Transmembrane34 – 5421Helical; Potential
Transmembrane59 – 7921Helical; Potential
Transmembrane103 – 12321Helical; Potential
Transmembrane148 – 16821Helical; Potential
Transmembrane179 – 19921Helical; Potential
Transmembrane220 – 24021Helical; Potential
Transmembrane259 – 27921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P80441 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: B48B99A2F21AC8AB

FASTA28131,652
        10         20         30         40         50         60 
MIEMYDRNYI YNMTTKIMNR SVQAHPFHLV EASPWPIAVS FSLLVVTLSG VMTFQGYSNG 

        70         80         90        100        110        120 
LFLLTLGFIS LVSTMTLWFK DISREGTFQG HHTFAVQKGL SLGFVLFVVS EVFFFISIFW 

       130        140        150        160        170        180 
AFFHSALAPT VELGAHWPPA GIETLNPWEV PLLNTVILLS SGATVTYAHH ANPSNRAGVI 

       190        200        210        220        230        240 
YGLIATIVLA TVFTGFQGFE YYNAPFTFSD GVYGSTFYMA TGFHGIHVLV GTIFLTVGLF 

       250        260        270        280 
RVLSYHLTDH HHLGFEQAIL YWHFVDVVWL FLFISVYWWG G 

« Hide

References

[1]"Molecular phylogeny of Allomyces macrogynus: congruency between nuclear ribosomal RNA- and mitochondrial protein-based trees."
Paquin B., Forget L., Roewer I., Lang B.F.
J. Mol. Evol. 41:657-665(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DAOM 148428.

Cross-references

3D structure databases

ProteinModelPortalP80441.
SMRP80441. Positions 23-281.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_RHIST
AccessionPrimary (citable) accession number: P80441
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families