Reviewed, UniProtKB/Swiss-Prot P80427 (TALDO_CARMA)

Names and origin

Protein names	Recommended name:     Transaldolase     EC=2.2.1.2
Organism	Carcinus maenas (Common shore crab) (Green crab)
Taxonomic identifier	6759 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Crustacea › Malacostraca › Eumalacostraca › Eucarida › Decapoda › Pleocyemata › Brachyura › Eubrachyura › Portunoidea › Portunidae › Carcinus

Protein attributes

Sequence length	75 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. May play a role in the conversion of sterols into ecdysteroids via NADPH.
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Subcellular location	Cytoplasm.
Tissue specificity	Predominantly expressed in Y-organs.
Post-translational modification	Phosphorylated.
Miscellaneous	On the 2D-gel the determined pI of this protein is: 6.8, its MW is: 36.2 kDa.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
PTM	Phosphoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›75	›75	Transaldolase		PRO_0000173568
Experimental info
	Non-adjacent residues	17 – 18	2
	Non-adjacent residues	27 – 28	2
	Non-adjacent residues	34 – 35	2
	Non-adjacent residues	48 – 49	2
	Non-adjacent residues	64 – 65	2
	Non-terminal residue	1	1
	Non-terminal residue	75	1

Sequences

	Sequence		Length	Mass (Da)
	P80427-1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: BD844CEF4EB50559	FASTA	75	8,818
	10 20 30 40 50 60 KYKPTDATTN PSLILQAKFL EELQNSKKIY NYYKKESVVE HLSESSAKKL EMTEANFRWE 70 MNEDKFAVDA VKLEK

References

[1]	"A transaldolase. An enzyme implicated in crab steroidogenesis." Lachaise F., Somme G., Carpentier G., Granjeon E., Webster S., Baghdassarian D. Endocrine 5:23-32(1996) Cited for: PROTEIN SEQUENCE.

Cross-references

3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.2.1.2. 19006.
Family and domain databases
InterPro	IPR001585. Transaldolase. IPR004730. Transaldolase_AB. IPR018225. Transaldolase_AS. [Graphical view]
PANTHER	PTHR10683. Transaldolase. 1 hit. PTHR10683:SF3. Transaldolase_AB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TALDO_CARMA

Accession

Primary (citable) accession number: P80427

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1997
Last modified:	June 16, 2009
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)