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Protein

Alpha-amylase inhibitor AAI

Gene

AAI

Organism
Amaranthus hypochondriacus (Prince-of-Wales feather) (Amaranthus hybridus var. hypochondriacus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Alpha-amylase inhibitor. It is active against alpha-amylases from Tribolium castaneum and Prostephanus truncatus larvae.

GO - Molecular functioni

Keywordsi

Molecular functionAlpha-amylase inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylase inhibitor AAI
Gene namesi
Name:AAI
OrganismiAmaranthus hypochondriacus (Prince-of-Wales feather) (Amaranthus hybridus var. hypochondriacus)
Taxonomic identifieri28502 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeAmaranthus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000841231 – 32Alpha-amylase inhibitor AAIAdd BLAST32

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi1 ↔ 181 Publication
Disulfide bondi8 ↔ 231 Publication
Disulfide bondi17 ↔ 311 Publication

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Endosperm.

Interactioni

Protein-protein interaction databases

MINTiP80403

Structurei

Secondary structure

132
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 8Combined sources3
Helixi10 – 13Combined sources4
Beta strandi26 – 31Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1CLVX-ray2.00I1-32[»]
1HTXNMR-A1-32[»]
1QFDNMR-A1-32[»]
ProteinModelPortaliP80403
SMRiP80403
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP80403

Family & Domainsi

Domaini

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.

Keywords - Domaini

Knottin

Family and domain databases

InterProiView protein in InterPro
IPR011052 Proteinase_amylase_inhib_sf
SUPFAMiSSF57027 SSF57027, 1 hit

Sequencei

Sequence statusi: Complete.

P80403-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
CIPKWNRCGP KMDGVPCCEP YTCTSDYYGN CS
Length:32
Mass (Da):3,592
Last modified:February 1, 1995 - v1
Checksum:i4B9B744B58C39BE3
GO

Sequence databases

PIRiA54845

Similar proteinsi

Entry informationi

Entry nameiIAAI_AMAHP
AccessioniPrimary (citable) accession number: P80403
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

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