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P80397

- GGN3_GLARU

UniProt

P80397 - GGN3_GLARU

Protein

Gaegurin-3

Gene

GGN3

Organism
Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.

    GO - Biological processi

    1. defense response to bacterium Source: UniProtKB-KW

    Keywords - Molecular functioni

    Amphibian defense peptide, Antibiotic, Antimicrobial

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Gaegurin-3
    Gene namesi
    Name:GGN3
    OrganismiGlandirana rugosa (Japanese wrinkled frog) (Rana rugosa)
    Taxonomic identifieri8410 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaRanoideaRanidaeGlandirana

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Peptidei1 – 3333Gaegurin-3PRO_0000044654Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi27 ↔ 33By similarity

    Keywords - PTMi

    Disulfide bond

    Expressioni

    Tissue specificityi

    Expressed by the skin glands.

    Interactioni

    Subunit structurei

    Monomer.

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR012521. Antimicrobial_frog_2.
    [Graphical view]
    PfamiPF08023. Antimicrobial_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P80397-1 [UniParc]FASTAAdd to Basket

    « Hide

    GIMSIVKDVA KTAAKEAAKG ALSTLSCKLA KTC                     33
    Length:33
    Mass (Da):3,309
    Last modified:November 1, 1995 - v1
    Checksum:iC1EA65E2489E5475
    GO

    Sequence databases

    PIRiPC2302.

    Cross-referencesi

    Sequence databases

    PIRi PC2302.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR012521. Antimicrobial_frog_2.
    [Graphical view ]
    Pfami PF08023. Antimicrobial_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
      Park J.M., Jung J.-E., Lee B.J.
      Biochem. Biophys. Res. Commun. 205:948-954(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Skin secretion.

    Entry informationi

    Entry nameiGGN3_GLARU
    AccessioniPrimary (citable) accession number: P80397
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3