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P80397

- GGN3_GLARU

UniProt

P80397 - GGN3_GLARU

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Protein

Gaegurin-3

Gene

GGN3

Organism
Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.

GO - Biological processi

  1. defense response to bacterium Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Amphibian defense peptide, Antibiotic, Antimicrobial

Names & Taxonomyi

Protein namesi
Recommended name:
Gaegurin-3
Gene namesi
Name:GGN3
OrganismiGlandirana rugosa (Japanese wrinkled frog) (Rana rugosa)
Taxonomic identifieri8410 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaRanoideaRanidaeGlandirana

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 3333Gaegurin-3PRO_0000044654Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi27 ↔ 33By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the skin glands.

Interactioni

Subunit structurei

Monomer.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR012521. Antimicrobial_frog_2.
[Graphical view]
PfamiPF08023. Antimicrobial_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P80397-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30
GIMSIVKDVA KTAAKEAAKG ALSTLSCKLA KTC
Length:33
Mass (Da):3,309
Last modified:November 1, 1995 - v1
Checksum:iC1EA65E2489E5475
GO

Sequence databases

PIRiPC2302.

Cross-referencesi

Sequence databases

PIRi PC2302.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR012521. Antimicrobial_frog_2.
[Graphical view ]
Pfami PF08023. Antimicrobial_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
    Park J.M., Jung J.-E., Lee B.J.
    Biochem. Biophys. Res. Commun. 205:948-954(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Tissue: Skin secretion.

Entry informationi

Entry nameiGGN3_GLARU
AccessioniPrimary (citable) accession number: P80397
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3