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Protein

30S ribosomal protein S18

Gene

rpsR

Organism
Thermus thermophilus
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.By similarity

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S18
Gene namesi
Name:rpsR
Synonyms:rps18
OrganismiThermus thermophilus
Taxonomic identifieri274 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 888730S ribosomal protein S18PRO_0000111251Add
BLAST

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6 (By similarity).By similarity

Structurei

Secondary structure

1
88
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni22 – 243Combined sources
Helixi37 – 404Combined sources
Helixi41 – 433Combined sources
Beta strandi46 – 483Combined sources
Helixi53 – 564Combined sources
Helixi60 – 7516Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TWTmodel-U1-88[»]
2VQEX-ray2.50R1-88[»]
2VQFX-ray2.90R1-88[»]
SMRiP80382. Positions 7-88.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP80382.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S18P family.Curated

Family and domain databases

Gene3Di4.10.640.10. 1 hit.
HAMAPiMF_00270. Ribosomal_S18.
InterProiIPR001648. Ribosomal_S18.
IPR018275. Ribosomal_S18_CS.
[Graphical view]
PANTHERiPTHR13479. PTHR13479. 1 hit.
PfamiPF01084. Ribosomal_S18. 1 hit.
[Graphical view]
PRINTSiPR00974. RIBOSOMALS18.
ProDomiPD002239. Ribosomal_S18. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46911. SSF46911. 1 hit.
TIGRFAMsiTIGR00165. S18. 1 hit.
PROSITEiPS00057. RIBOSOMAL_S18. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P80382-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKNAKPKK EAQRRPSRKA KVKATLGEFD LRDYRNVEVL KRFLSETGKI
60 70 80
LPRRRTGLSG KEQRILAKTI KRARILGLLP FTEKLVRK
Length:88
Mass (Da):10,217
Last modified:January 22, 2007 - v3
Checksum:iCFDE7AC4935E9E09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF146075 Genomic DNA. Translation: AAF27297.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF146075 Genomic DNA. Translation: AAF27297.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TWTmodel-U1-88[»]
2VQEX-ray2.50R1-88[»]
2VQFX-ray2.90R1-88[»]
SMRiP80382. Positions 7-88.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP80382.

Family and domain databases

Gene3Di4.10.640.10. 1 hit.
HAMAPiMF_00270. Ribosomal_S18.
InterProiIPR001648. Ribosomal_S18.
IPR018275. Ribosomal_S18_CS.
[Graphical view]
PANTHERiPTHR13479. PTHR13479. 1 hit.
PfamiPF01084. Ribosomal_S18. 1 hit.
[Graphical view]
PRINTSiPR00974. RIBOSOMALS18.
ProDomiPD002239. Ribosomal_S18. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF46911. SSF46911. 1 hit.
TIGRFAMsiTIGR00165. S18. 1 hit.
PROSITEiPS00057. RIBOSOMAL_S18. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequencing and analysis of the Thermus thermophilus gene cluster equivalent to the S6 operon."
    Shcherbakov D.V., Cherepanova E.A., Garber M.B.
    Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: VK1.

Entry informationi

Entry nameiRS18_THETH
AccessioniPrimary (citable) accession number: P80382
Secondary accession number(s): Q9LCZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 1995
Last sequence update: January 22, 2007
Last modified: March 31, 2015
This is version 88 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.