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P80376 (RS11_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 119. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S11
Gene names
Name:rpsK
Synonyms:rps11
Ordered Locus Names:TTHA1666
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length129 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Located on the upper part of the platform of the 30S subunit, where it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome, where it interacts both with the Shine-Dalgarno helix and mRNA. HAMAP-Rule MF_01310

Subunit structure

Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to the C-terminus of IF-3; however exactly how IF-3 interacts with the 30S subunit is unclear. May contact the C-terminus of Era. Ref.5 Ref.6 Ref.7 Ref.8 Ref.10 Ref.11 Ref.13 Ref.14 Ref.15

Sequence similarities

Belongs to the ribosomal protein S11P family.

Mass spectrometry

Molecular mass is 13583 Da from positions 2 - 129. Determined by MALDI. Ref.4

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3
Chain2 – 12912830S ribosomal protein S11 HAMAP-Rule MF_01310
PRO_0000123246

Secondary structure

............................ 129
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P80376 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 028E047E6DCE3CA2

FASTA12913,713
        10         20         30         40         50         60 
MAKKPSKKKV KRQVASGRAY IHASYNNTIV TITDPDGNPI TWSSGGVIGY KGSRKGTPYA 

        70         80         90        100        110        120 
AQLAALDAAK KAMAYGMQSV DVIVRGTGAG REQAIRALQA SGLQVKSIVD DTPVPHNGCR 


PKKKFRKAS 

« Hide

References

« Hide 'large scale' references
[1]"Cloning of the RNA polymerase alpha subunit gene from Thermus thermophilus HB8 and characterization of the protein."
Wada T., Yamazaki T., Kuramitsu S., Kyogoku Y.
J. Biochem. 125:143-150(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[3]"Purification and characterization of the 30S ribosomal proteins from the bacterium Thermus thermophilus."
Tsiboli P., Herfurth E., Choli T.
Eur. J. Biochem. 226:169-177(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-26.
[4]"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: MASS SPECTROMETRY.
[5]"Structure of the 30S ribosomal subunit."
Wimberly B.T., Brodersen D.E., Clemons W.M. Jr., Morgan-Warren R.J., Carter A.P., Vonrhein C., Hartsch T., Ramakrishnan V.
Nature 407:327-339(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
[6]"Structure of functionally activated small ribosomal subunit at 3.3 A resolution."
Schluenzen F., Tocilj A., Zarivach R., Harms J., Gluehmann M., Janell D., Bashan A., Bartels H., Agmon I., Franceschi F., Yonath A.
Cell 102:615-623(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[7]"The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Cell 103:1143-1154(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[8]"Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Nature 407:340-348(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 30S SUBUNIT.
[9]"The path of messenger RNA through the ribosome."
Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[10]"Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3."
Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F.
EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[11]"Crystal structure of an initiation factor bound to the 30S ribosomal subunit."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Hartsch T., Wimberly B.T., Ramakrishnan V.
Science 291:498-501(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[12]"Crystal structure of the ribosome at 5.5 A resolution."
Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F.
Science 292:883-896(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
[13]"Recognition of cognate transfer RNA by the 30S ribosomal subunit."
Ogle J.M., Brodersen D.E., Clemons W.M. Jr., Tarry M.J., Carter A.P., Ramakrishnan V.
Science 292:897-902(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.11 ANGSTROMS) OF THE 30S SUBUNIT.
[14]"Crystal structure of the 30S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16S RNA."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Wimberly B.T., Ramakrishnan V.
J. Mol. Biol. 316:725-768(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
[15]"Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly."
Sharma M.R., Barat C., Wilson D.N., Booth T.M., Kawazoe M., Hori-Takemoto C., Shirouzu M., Yokoyama S., Fucini P., Agrawal R.K.
Mol. Cell 18:319-329(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY ELECTRON MICROSCOPY (13.50 ANGSTROMS), POSSIBLE INTERACTION WITH ERA.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB024328 Genomic DNA. Translation: BAA75547.1.
AP008226 Genomic DNA. Translation: BAD71489.1.
RefSeqYP_144932.1. NC_006461.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1FJGX-ray3.00K1-129[»]
1GIXX-ray5.50N1-129[»]
1HNWX-ray3.40K1-129[»]
1HNXX-ray3.40K1-129[»]
1HNZX-ray3.30K1-129[»]
1HR0X-ray3.20K1-129[»]
1I94X-ray3.20K2-129[»]
1I95X-ray4.50K2-129[»]
1I96X-ray4.20K2-129[»]
1I97X-ray4.50K2-129[»]
1IBKX-ray3.31K1-129[»]
1IBLX-ray3.11K1-129[»]
1IBMX-ray3.31K1-129[»]
1J5EX-ray3.05K1-129[»]
1JGOX-ray5.60N1-129[»]
1JGPX-ray7.00N1-129[»]
1JGQX-ray5.00N1-129[»]
1L1Umodel-K11-129[»]
1ML5electron microscopy14.00N1-129[»]
1N32X-ray3.00K1-129[»]
1N33X-ray3.35K1-129[»]
1N34X-ray3.80K1-129[»]
1N36X-ray3.65K1-129[»]
1PNSX-ray8.70K11-129[»]
1PNXX-ray9.50K11-129[»]
1X18electron microscopy13.50G11-129[»]
1XMOX-ray3.25K1-129[»]
1XMQX-ray3.00K1-129[»]
1XNQX-ray3.05K1-129[»]
1XNRX-ray3.10K1-129[»]
1YL4X-ray5.50N1-129[»]
2B64X-ray5.90K1-129[»]
2B9MX-ray6.76K1-129[»]
2B9OX-ray6.46K1-129[»]
2E5LX-ray3.30K2-129[»]
2F4VX-ray3.80K1-129[»]
2HGIX-ray5.00N1-129[»]
2HGPX-ray5.50N1-129[»]
2HGRX-ray4.51N1-129[»]
2HHHX-ray3.35K1-129[»]
2J00X-ray2.80K2-129[»]
2J02X-ray2.80K2-129[»]
2OW8X-ray3.71l-[»]
2UU9X-ray3.10K2-129[»]
2UUAX-ray2.90K2-129[»]
2UUBX-ray2.90K2-129[»]
2UUCX-ray3.10K2-129[»]
2UXBX-ray3.10K2-129[»]
2UXCX-ray2.90K2-129[»]
2UXDX-ray3.20K2-129[»]
2V46X-ray3.50K2-129[»]
2V48X-ray3.50K2-129[»]
2VQEX-ray2.50K1-129[»]
2VQFX-ray2.90K1-129[»]
2WDGX-ray3.30K1-129[»]
2WDHX-ray3.30K1-129[»]
2WDKX-ray3.50K1-129[»]
2WDMX-ray3.50K1-129[»]
2WH1X-ray3.45K1-129[»]
2WH3X-ray3.45K1-129[»]
2WRIX-ray3.60K1-129[»]
2WRKX-ray3.60K1-129[»]
2WRNX-ray3.60K1-129[»]
2WRQX-ray3.60K1-129[»]
2X9RX-ray3.10K1-129[»]
2X9TX-ray3.10K1-129[»]
2XFZX-ray3.20K1-129[»]
2XG1X-ray3.20K1-129[»]
2XQDX-ray3.10K1-129[»]
2XSYelectron microscopy7.80K1-129[»]
2XUYelectron microscopy7.60K1-129[»]
2Y0UX-ray3.10K1-129[»]
2Y0WX-ray3.10K1-129[»]
2Y0YX-ray3.10K1-129[»]
2Y10X-ray3.10K1-129[»]
2Y12X-ray3.10K1-129[»]
2Y14X-ray3.10K1-129[»]
2Y16X-ray3.10K1-129[»]
2Y18X-ray3.10K1-129[»]
2ZM6X-ray3.30K2-129[»]
3FICelectron microscopy6.40K11-129[»]
3HUWX-ray3.10K1-129[»]
3HUYX-ray3.10K1-129[»]
3I8GX-ray3.10N1-129[»]
3I8HX-ray3.10N1-129[»]
3I9BX-ray3.50N1-129[»]
3I9DX-ray3.50N1-129[»]
3KIQX-ray3.30k1-129[»]
3KISX-ray3.30k1-129[»]
3KIUX-ray3.60k1-129[»]
3KIXX-ray3.60k1-129[»]
3KNHX-ray3.00K1-129[»]
3KNJX-ray3.15K1-129[»]
3KNLX-ray3.45K1-129[»]
3KNNX-ray3.45K1-129[»]
3OGEX-ray3.00K1-129[»]
3OGYX-ray3.00K1-129[»]
3OHCX-ray3.00K1-129[»]
3OHDX-ray3.00K1-129[»]
3OHYX-ray3.00K1-129[»]
3OI0X-ray3.00K1-129[»]
3OI2X-ray3.10K1-129[»]
3OI4X-ray3.10K1-129[»]
3OTOX-ray3.69K1-129[»]
3T1HX-ray3.11K1-129[»]
3T1YX-ray2.80K1-129[»]
3TVFX-ray3.10N1-129[»]
3TVGX-ray3.10N1-129[»]
3UXSX-ray3.20K1-129[»]
3UXTX-ray3.20K1-129[»]
3UYDX-ray3.00N1-129[»]
3UYFX-ray3.00N1-129[»]
3UZ3X-ray3.30N1-129[»]
3UZ4X-ray3.30N1-129[»]
3UZ6X-ray3.00N1-129[»]
3UZ7X-ray3.00N1-129[»]
3UZGX-ray3.30N1-129[»]
3UZIX-ray3.30N1-129[»]
3UZLX-ray3.30N1-129[»]
3UZMX-ray3.30N1-129[»]
3V22X-ray3.00K1-129[»]
3V24X-ray3.00K1-129[»]
3V26X-ray3.10K1-129[»]
3V28X-ray3.10K1-129[»]
3V2CX-ray2.70K1-129[»]
3V2EX-ray2.70K1-129[»]
3V6UX-ray3.90K1-129[»]
3V6VX-ray3.90K1-129[»]
3ZN7X-ray3.10K1-129[»]
3ZNDX-ray3.10K1-129[»]
3ZVOX-ray3.80K1-129[»]
4ABRX-ray3.10K1-129[»]
4AQYX-ray3.50K1-129[»]
4B3MX-ray2.90K1-129[»]
4B3RX-ray3.00K1-129[»]
4B3SX-ray3.15K1-129[»]
4B3TX-ray3.00K1-129[»]
4B8FX-ray3.70K1-129[»]
4B8HX-ray3.70K1-129[»]
4BYBX-ray3.35K1-129[»]
4BYDX-ray3.35K1-129[»]
4CR1X-ray2.95K1-129[»]
4DH9X-ray3.20K1-129[»]
4DHBX-ray3.20K1-129[»]
4DR1X-ray3.60K1-129[»]
4DR2X-ray3.25K1-129[»]
4DR3X-ray3.35K1-129[»]
4DR4X-ray3.97K1-129[»]
4DR5X-ray3.45K1-129[»]
4DR6X-ray3.30K1-129[»]
4DR7X-ray3.75K1-129[»]
4DUYX-ray3.39K1-129[»]
4DUZX-ray3.65K1-129[»]
4DV0X-ray3.85K1-129[»]
4DV1X-ray3.85K1-129[»]
4DV2X-ray3.65K1-129[»]
4DV3X-ray3.55K1-129[»]
4DV4X-ray3.65K1-129[»]
4DV5X-ray3.68K1-129[»]
4DV6X-ray3.30K1-129[»]
4DV7X-ray3.29K1-129[»]
4EJ9X-ray3.52K1-129[»]
4EJAX-ray3.52K1-129[»]
4G5KX-ray3.30N1-129[»]
4G5MX-ray3.30N1-129[»]
4G5TX-ray3.10N1-129[»]
4G5VX-ray3.10N1-129[»]
4GKJX-ray3.30K11-129[»]
4GKKX-ray3.20K11-129[»]
4JI0X-ray3.49K1-129[»]
4JI1X-ray3.14K1-129[»]
4JI2X-ray3.64K1-129[»]
4JI3X-ray3.35K1-129[»]
4JI4X-ray3.69K1-129[»]
4JI5X-ray3.85K1-129[»]
4JI6X-ray3.55K1-129[»]
4JI7X-ray3.50K1-129[»]
4JI8X-ray3.74K1-129[»]
4JUWX-ray2.86K11-129[»]
4JV5X-ray3.16K11-129[»]
4JYAX-ray3.10K11-129[»]
4K0KX-ray3.40K11-129[»]
4K0LX-ray3.30K11-129[»]
4K0PX-ray3.30K11-129[»]
4KHPX-ray3.10K11-129[»]
4NVUX-ray3.00K1-129[»]
4NVWX-ray3.00K1-129[»]
4NVYX-ray3.10K1-129[»]
4NW0X-ray3.10K1-129[»]
4NXMX-ray3.65K1-129[»]
4NXNX-ray3.54K1-129[»]
4OX9X-ray3.80K1-129[»]
ProteinModelPortalP80376.
SMRP80376. Positions 7-129.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA1666.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD71489; BAD71489; BAD71489.
GeneID3168024.
KEGGttj:TTHA1666.
PATRIC23958287. VBITheThe93045_1636.

Phylogenomic databases

eggNOGCOG0100.
HOGENOMHOG000111597.
KOK02948.
OMAHISASFN.
OrthoDBEOG6ZSPF3.
PhylomeDBP80376.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-1705-MONOMER.

Family and domain databases

Gene3D3.30.420.80. 1 hit.
HAMAPMF_01310. Ribosomal_S11.
InterProIPR001971. Ribosomal_S11.
IPR019981. Ribosomal_S11_bac-type.
IPR018102. Ribosomal_S11_CS.
[Graphical view]
PANTHERPTHR11759. PTHR11759. 1 hit.
PfamPF00411. Ribosomal_S11. 1 hit.
[Graphical view]
PIRSFPIRSF002131. Ribosomal_S11. 1 hit.
TIGRFAMsTIGR03632. bact_S11. 1 hit.
PROSITEPS00054. RIBOSOMAL_S11. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP80376.

Entry information

Entry nameRS11_THET8
AccessionPrimary (citable) accession number: P80376
Secondary accession number(s): Q5SHR4, Q9RA66
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 119 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references