P80333 (CX7A1_ONCMY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Cytochrome c oxidase subunit 7A-liver, mitochondrial EC=1.9.3.1 Alternative name(s): Cytochrome c oxidase subunit VIIa-liver
Organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomic identifier	8022 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Protacanthopterygii › Salmoniformes › Salmonoidei › Salmonidae › Salmoninae › Oncorhynchus

Protein attributes

Sequence length	23 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subcellular location	Mitochondrion inner membrane.
Sequence similarities	Belongs to the cytochrome c oxidase VIIa family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	mitochondrial respiratory chain Inferred from electronic annotation. Source: InterPro
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›23	›23	Cytochrome c oxidase subunit 7A-liver, mitochondrial		PRO_0000221002
Experimental info
	Non-terminal residue	23	1

Sequences

	Sequence		Length	Mass (Da)
	P80333 [UniParc]. Last modified October 1, 1994. Version 1. Checksum: BCBED43FBAD9C509	FASTA	23	2,636
	10 20 VDNMVPEKQK LFQAXNGIPV HLF

References

[1]	"Identification of tissue-specific isoforms for subunits Vb and VIIa of cytochrome c oxidase isolated from rainbow trout." Freund R., Kadenbach B. Eur. J. Biochem. 221:1111-1116(1994) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Liver.

Cross-references

Sequence databases
PIR	S43632.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	4.10.91.10. 1 hit.
InterPro	IPR003177. Cyt_c_oxidase_su7a. [Graphical view]
Pfam	PF02238. COX7a. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CX7A1_ONCMY

Accession

Primary (citable) accession number: P80333

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1994
Last sequence update:	October 1, 1994
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program