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P80268 (NUO2_SOLTU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADH-ubiquinone oxidoreductase 18 kDa subunit

EC=1.6.5.3
EC=1.6.99.3
Alternative name(s):
Complex I-18kD
Short name=CI-18kD
OrganismSolanum tuberosum (Potato) [Reference proteome]
Taxonomic identifier4113 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Protein attributes

Sequence length30 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Catalytic activity

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).

NADH + acceptor = NAD+ + reduced acceptor.

Subunit structure

Complex I is composed of about 45 different subunits By similarity.

Subcellular location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   LigandNAD
Ubiquinone
   Molecular functionOxidoreductase
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componentmitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›30›30NADH-ubiquinone oxidoreductase 18 kDa subunit
PRO_0000118850

Experimental info

Non-terminal residue301

Sequences

Sequence LengthMass (Da)Tools
P80268 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: 21AA88B3FAEDFE1D

FASTA303,263
        10         20         30 
ASEALVEIKP GEIGMVSGIP DEHLRRFVVI 

« Hide

References

[1]"New insights into the composition, molecular mass and stoichiometry of the protein complexes of plant mitochondria."
Jansch L., Kruft V., Schmitz U.K., Braun H.P.
Plant J. 9:357-368(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Tuber.
[2]"Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum."
Herz U., Schroeder W., Liddell A., Leaver C.J., Brennicke A., Grohmann L.
J. Biol. Chem. 269:2263-2269(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-22.
Strain: cv. Bintje.
Tissue: Tuber.

Cross-references

Sequence databases

PIRH49732.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameNUO2_SOLTU
AccessionPrimary (citable) accession number: P80268
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program