Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P80264

- NDUS2_SOLTU

UniProt

P80264 - NDUS2_SOLTU

Protein

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2

Gene

NAD7

Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme.By similarity

    Catalytic activityi

    NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
    NADH + acceptor = NAD+ + reduced acceptor.

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 (EC:1.6.5.3, EC:1.6.99.3)
    Alternative name(s):
    Complex I-42.5kD
    Short name:
    CI-42.5kD
    NADH dehydrogenase subunit 7
    NADH-ubiquinone oxidoreductase 42.5 kDa subunit
    Gene namesi
    Name:NAD7
    Encoded oniMitochondrion
    OrganismiSolanum tuberosum (Potato)
    Taxonomic identifieri4113 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
    ProteomesiUP000011115: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: UniProtKB-SubCell
    2. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – ›47›46NADH dehydrogenase [ubiquinone] iron-sulfur protein 2PRO_0000118586Add
    BLAST

    Interactioni

    Subunit structurei

    Complex I is composed of about 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP80264.
    SMRiP80264. Positions 20-47.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I 49 kDa subunit family.Curated

    Family and domain databases

    Gene3Di1.10.645.10. 1 hit.
    InterProiIPR029014. NiFe_Hase-like.
    [Graphical view]
    SUPFAMiSSF56762. SSF56762. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P80264-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTKNRQIQN FTLNFGPQHP AAHGVLRLVL EMNGEVVERA EPHIGLL      47
    Length:47
    Mass (Da):5,278
    Last modified:January 23, 2007 - v3
    Checksum:i0494931B92D06A87
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei47 – 471

    RNA editingi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75579 Genomic DNA. Translation: CAA53256.1. Sequence problems.
    PIRiS46439. S38586.

    Keywords - Coding sequence diversityi

    RNA editing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75579 Genomic DNA. Translation: CAA53256.1 . Sequence problems.
    PIRi S46439. S38586.

    3D structure databases

    ProteinModelPortali P80264.
    SMRi P80264. Positions 20-47.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.645.10. 1 hit.
    InterProi IPR029014. NiFe_Hase-like.
    [Graphical view ]
    SUPFAMi SSF56762. SSF56762. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The 42.5 kDa subunit of the NADH: ubiquinone oxidoreductase (complex I) in higher plants is encoded by the mitochondrial nad7 gene."
      Gabler L., Herz U., Liddell A., Leaver C.J., Schroeder W., Brennicke A., Grohmann L.
      Mol. Gen. Genet. 244:33-40(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], RNA EDITING.
      Tissue: Tuber.
    2. "Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum."
      Herz U., Schroeder W., Liddell A., Leaver C.J., Brennicke A., Grohmann L.
      J. Biol. Chem. 269:2263-2269(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-37.
      Strain: cv. Bintje.
      Tissue: Tuber.

    Entry informationi

    Entry nameiNDUS2_SOLTU
    AccessioniPrimary (citable) accession number: P80264
    Secondary accession number(s): Q43185
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 83 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3