Reviewed,
UniProtKB/Swiss-Prot P80264 (NDUS2_SOLTU)
Last modified
November 4, 2008.
Version 61.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: NADH-ubiquinone oxidoreductase 49 kDa subunit EC=1.6.5.3 EC=1.6.99.3 Alternative name(s): NADH dehydrogenase subunit 7 Complex I-42.5 kDa Short name=CI-42.5kD | ||
| Gene names |
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| Encoded on | Mitochondrion | ||
| Organism | Solanum tuberosum (Potato) | ||
| Taxonomic identifier | 4113 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum |
Protein attributes
| Sequence length | 47 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme. |
| Catalytic activity | NADH + ubiquinone = NAD(+) + ubiquinol. NADH + acceptor = NAD(+) + reduced acceptor. |
| Subunit structure | Complex I is composed of about 30 different subunits. This is a component of the iron-sulfur protein fraction. |
| Subcellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Sequence similarities | Belongs to the complex I 49 kDa subunit family. |
| RNA editing | Edited at positions 13, 26 and 28. |
Ontologies
Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Membrane Mitochondrion Mitochondrion inner membrane |
| Coding sequence diversity | RNA editing |
| Ligand | NAD Ubiquinone |
| Molecular function | Oxidoreductase |
| Technical term | Direct protein sequencing |
Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrial respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "The 42.5 kDa subunit of the NADH: ubiquinone oxidoreductase (complex I) in higher plants is encoded by the mitochondrial nad7 gene." Gabler L., Herz U., Liddell A., Leaver C.J., Schroeder W., Brennicke A., Grohmann L. Mol. Gen. Genet. 244:33-40(1994) [PubMed: 8041359] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], RNA EDITING. Tissue: Tuber. |
| [2] | "Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum." Herz U., Schroeder W., Liddell A., Leaver C.J., Brennicke A., Grohmann L. J. Biol. Chem. 269:2263-2269(1994) [PubMed: 8294484] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-37. Strain: cv. Bintje. Tissue: Tuber. |
Cross-references
Sequence databases | |
|---|---|
| X75579 Genomic DNA. Translation: CAA53256.1. Sequence problems. | |
| PIR | S38586. S46439. |
3D structure databases | |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR014029. NADH-UbQ_OxRdtase_49kDa_CS. [Graphical view] |
| PROSITE | PS00535. COMPLEX1_49K. Partial match. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NDUS2_SOLTU | ||||||||
| Accession | Primary (citable) accession number: P80264 Secondary accession number(s): Q43185 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||

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