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Reviewed, UniProtKB/Swiss-Prot P80261 (NDUS3_SOLTU)

Last modified November 25, 2008. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    NADH-ubiquinone oxidoreductase 27 kDa subunit
    EC=1.6.5.3
    EC=1.6.99.3
Alternative name(s):
    Complex I-27 kDa
      Short name=CI-27kD
    NADH dehydrogenase subunit 9
Gene names
Name: NAD9
Encoded onMitochondrion
OrganismSolanum tuberosum (Potato)
Taxonomic identifier4113 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.

Catalytic activity

NADH + ubiquinone = NAD(+) + ubiquinol.

NADH + acceptor = NAD(+) + reduced acceptor.

Subunit structure

Complex I is composed of about 30 different subunits.

Subcellular location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Sequence similarities

Belongs to the complex I 30 kDa subunit family.

RNA editing

Edited at positions 31, 56, 100, 110, 122, 133 and 147.

Ontologies

Keywords

   Biological processElectron transport
Respiratory chain
Transport
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   Coding sequence diversityRNA editing
   LigandNAD
Ubiquinone
   Molecular functionOxidoreductase
   Technical termDirect protein sequencing

Gene Ontology (GO)

   Biological processmitochondrial electron transport, NADH to ubiquinone

Inferred from electronic annotation. Source: InterPro

transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrial respiratory chain

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 190190NADH-ubiquinone oxidoreductase 27 kDa subunit
PRO_0000118643

Sequences

Sequence LengthMass (Da)Tools
P80261-1 [UniParc].

Last modified November 28, 2003. Version 3.
Checksum: A150CF461B493A53

FASTA19022,883
        10         20         30         40         50         60 
MDNQFIFKYS WETLPKKWVK KMERSEHGNR FDTNTDYLFQ LLCFMKLHTY TRVQVLIDIC 

        70         80         90        100        110        120 
GVDYPSRKQR FEVVYNLLSI RYNSRIRVQT SADEVTRISS VVSLFPSAGW WEREVWDMFG 

       130        140        150        160        170        180 
VFSINHPDLR RILTDYGFEG HPLRKDFPLS GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF 

       190 
ASPWEQRSDG 

« Hide

References

[1]"Translation of nad9 mRNAs in mitochondria from Solanum tuberosum is restricted to completely edited transcripts."
Grohmann L., Thieck O., Herz U., Schroeder W., Brennicke A.
Nucleic Acids Res. 22:3304-3311(1994) [PubMed: 8078764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, RNA EDITING.
Tissue: Tuber.
[2]"Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum."
Herz U., Schroeder W., Liddell A., Leaver C.J., Brennicke A., Grohmann L.
J. Biol. Chem. 269:2263-2269(1994) [PubMed: 8294484] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-17.
Strain: cv. Bintje.
Tissue: Tuber.

Cross-references

Sequence databases

X79774 Genomic DNA. Translation: CAA56168.1. Sequence problems.
PIRS48062.

3D structure databases

ModBaseSearch...

Family and domain databases

InterProIPR010218. NADH_DH_csu.
IPR001268. NADH_DHase_Ub_30kDa_su.
[Graphical view]
PfamPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomPD001581. Complex1_30K. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01961. NuoC_fam. 1 hit.
PROSITEPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNDUS3_SOLTU
AccessionPrimary (citable) accession number: P80261
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 28, 2003
Last modified: November 25, 2008
This is version 56 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents