Reviewed, UniProtKB/Swiss-Prot P80232 (CU70_LOCMI)

Names and origin

Protein names	Recommended name:     Cuticle protein 70, isoforms A and B Alternative name(s):     LM-70A/LM-70B
Organism	Locusta migratoria (Migratory locust)
Taxonomic identifier	7004 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Orthopteroidea › Orthoptera › Caelifera › Acridomorpha › Acridoidea › Acrididae › Oedipodinae › Locusta

Protein attributes

Sequence length	88 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
Domain	The tetrapeptide (A-A-P-[AV]) repeats found throughout the protein are also present in many proteins constituting the protective envelope of other species.
Miscellaneous	The sequence shown here is that of isoform LM-70A.

Ontologies

Keywords
Cellular component	Cuticle
Domain	Repeat
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 88	88	Cuticle protein 70, isoforms A and B		PRO_0000196112
Regions
	Repeat	7 – 10	4	1
	Repeat	48 – 51	4	2
	Repeat	55 – 58	4	3
	Repeat	60 – 63	4	4
	Repeat	66 – 69	4	5
Natural variations
	Natural variant	82	1	F → Y in isoform LM-70B.

Sequences

	Sequence		Length	Mass (Da)
	P80232-1 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 6F6B8359FD691B01	FASTA	88	8,314
	10 20 30 40 50 60 GYLGGYAAPA VAVAPAPALA VAHAPAVVVA TSYARISQVT NSVPIAVAAP AVPKAAVPVA 70 80 APVVAAAPVI AAHAPLALGH GFGYGGYH

References

[1]

"Combined plasma-desorption mass spectrometry and Edman degradation applied to simultaneous sequence determination of isoforms of structural proteins from the cuticle of Locusta migratoria." Andreasen L., Hoejrup P., Andersen S.O., Roepstorff P. Eur. J. Biochem. 217:267-273(1993) [PubMed: 8223564] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
PIR	S38267.
3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CU70_LOCMI

Accession

Primary (citable) accession number: P80232

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	November 25, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)