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Protein

Allergen Bra j 1-E

Gene
N/A
Organism
Brassica juncea (Indian mustard) (Sinapis juncea)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This is a 2S seed storage protein.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Seed storage protein, Storage protein

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Bra j 1-E
Alternative name(s):
Allergen Bra j I
Allergen: Bra j 1-E
Cleaved into the following 2 chains:
OrganismiBrassica juncea (Indian mustard) (Sinapis juncea)
Taxonomic identifieri3707 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei168. Bra j 1.
3161. Bra j 1.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3737Allergen Bra j 1-E small chainPRO_0000032170Add
BLAST
Chaini38 – 12992Allergen Bra j 1-E large chainPRO_0000032171Add
BLAST

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

The mature protein consists of a small and a large chain linked by two disulfide bonds.

Structurei

3D structure databases

ProteinModelPortaliP80207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2S seed storage albumins family.Curated

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000617. Napin.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00496. NAPIN.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P80207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AGPFRFPRCR KEFQQAQHLR ACQQWLHKQA MQSGSGPQPQ GPQQRPPLLQ
60 70 80 90 100
QCCNELHQEE PLCVCPTLKG ASKAVKQQIR QQGQQQGQQG QQLQHEISRI
110 120
YQTATHLPRV CNIPRVSICP FQKTMPGPS
Length:129
Mass (Da):14,644
Last modified:October 1, 1993 - v1
Checksum:iD6F28E03F62B08F8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-adjacent residuesi37 – 382Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti6 – 61F → I.
Natural varianti20 – 201R → K.

Sequence databases

PIRiS35591.
S35592.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

PIRiS35591.
S35592.

3D structure databases

ProteinModelPortaliP80207.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei168. Bra j 1.
3161. Bra j 1.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000617. Napin.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00496. NAPIN.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiALL1_BRAJU
AccessioniPrimary (citable) accession number: P80207
Secondary accession number(s): P80215
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.