P80207 (ALL1_BRAJU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Allergen Bra j 1-E Alternative name(s): Allergen Bra j I Allergen=Bra j 1-E Cleaved into the following 2 chains: Allergen Bra j 1-E small chain Allergen Bra j 1-E large chain
Organism	Brassica juncea (Indian mustard) (Sinapis juncea)
Taxonomic identifier	3707 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Brassiceae › Brassica

Protein attributes

Sequence length	129 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This is a 2S seed storage protein.
Subunit structure	The mature protein consists of a small and a large chain linked by two disulfide bonds.
Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the 2S seed storage albumins family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Disease	Allergen
Molecular function	Seed storage protein Storage protein
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	nutrient reservoir activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 37	37	Allergen Bra j 1-E small chain		PRO_0000032170
	Chain	38 – 129	92	Allergen Bra j 1-E large chain		PRO_0000032171
Natural variations
	Natural variant	6	1	F → I.
	Natural variant	20	1	R → K.
Experimental info
	Non-adjacent residues	37 – 38	2

Sequences

	Sequence		Length	Mass (Da)
	P80207 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: D6F28E03F62B08F8	FASTA	129	14,644
	10 20 30 40 50 60 AGPFRFPRCR KEFQQAQHLR ACQQWLHKQA MQSGSGPQPQ GPQQRPPLLQ QCCNELHQEE 70 80 90 100 110 120 PLCVCPTLKG ASKAVKQQIR QQGQQQGQQG QQLQHEISRI YQTATHLPRV CNIPRVSICP FQKTMPGPS

References

[1]	"Characterization of a new oriental-mustard (Brassica juncea) allergen, Bra j IE: detection of an allergenic epitope." Monsalve R.I., Gonzalez de la Pena M.A., Menendez-Arias L., Lopez-Otin C., Villalba M., Rodriguez R. Biochem. J. 293:625-632(1993) [PubMed: 7688955] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Seed.
+	Additional computationally mapped references.

Cross-references

Sequence databases
PIR	S35591. S35592.
3D structure databases
ProteinModelPortal	P80207.
ModBase	Search...
Protein family/group databases
Allergome	168. Bra j 1. 3161. Bra j 1.0101.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR016140. Bifunc_inhib/LTP/seed_store. IPR003612. LTP/seed_store/tryp_amyl_inhib. IPR000617. Napin. IPR013771. Trypsin/amylase_inhib. [Graphical view]
Gene3D	G3DSA:1.10.120.10. Trypsin/amylase_inhib. 1 hit.
Pfam	PF00234. Tryp_alpha_amyl. 1 hit. [Graphical view]
PRINTS	PR00496. NAPIN.
SMART	SM00499. AAI. 1 hit. [Graphical view]
SUPFAM	SSF47699. Bifunc_inhib/LTP/seed_store. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALL1_BRAJU

Accession

Primary (citable) accession number: P80207
Secondary accession number(s): P80215

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	September 21, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program