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P80176 (HIP_THETI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
High-potential iron-sulfur protein

Short name=HiPIP
Gene names
Name:hip
OrganismThermochromatium tepidum (Chromatium tepidum)
Taxonomic identifier1050 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeThermochromatium

Protein attributes

Sequence length83 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

Subunit structure

Homodimer Probable.

Sequence similarities

Belongs to the high-potential iron-sulfur protein (HiPIP) family.

Biophysicochemical properties

Redox potential:

E0 is +323 mV.

Temperature dependence:

Thermostable.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8383High-potential iron-sulfur protein
PRO_0000220429

Sites

Metal binding431Iron-sulfur (4Fe-4S)
Metal binding461Iron-sulfur (4Fe-4S)
Metal binding611Iron-sulfur (4Fe-4S)
Metal binding751Iron-sulfur (4Fe-4S)

Secondary structure

.................. 83
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P80176 [UniParc].

Last modified October 1, 1993. Version 1.
Checksum: 92116E4FD2C44E0A

FASTA838,786
        10         20         30         40         50         60 
AAPANAVTAD DPTAIALKYN QDATKSERVA AARPGLPPEE QHCANCQFMQ ANVGEGDWKG 

        70         80 
CQLFPGKLIN VNGWCASWTL KAG 

« Hide

References

[1]"Primary structure of Chromatium tepidum high-potential iron-sulfur protein in relation to thermal denaturation."
Moulis J.-M., Scherrer N., Gagnon J., Forest E., Petillot Y., Garcia D.
Arch. Biochem. Biophys. 305:186-192(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: ATCC 43061 / DSM 3771 / MC.
[2]"Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer."
Nogi T., Fathir I., Kobayashi M., Nozawa T., Miki K.
Proc. Natl. Acad. Sci. U.S.A. 97:13561-13566(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS).
[3]"Ultrahigh-resolution structure of high-potential iron-sulfur protein from Thermochromatium tepidum."
Liu L., Nogi T., Kobayashi M., Nozawa T., Miki K.
Acta Crystallogr. D 58:1085-1091(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (0.8 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

PIRS35586.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1EYTX-ray1.50A1-83[»]
1IUAX-ray0.80A1-83[»]
2AMSX-ray1.40A1-83[»]
2FLAX-ray0.95A1-83[»]
3A38X-ray0.70A1-83[»]
3A39X-ray0.72A1-83[»]
ProteinModelPortalP80176.
SMRP80176. Positions 1-83.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D4.10.490.10. 1 hit.
InterProIPR000170. High_potential_FeS_prot.
[Graphical view]
PfamPF01355. HIPIP. 1 hit.
[Graphical view]
SUPFAMSSF57652. SSF57652. 1 hit.
PROSITEPS51373. HIPIP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP80176.

Entry information

Entry nameHIP_THETI
AccessionPrimary (citable) accession number: P80176
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 16, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references