true1993-04-012024-03-2781FRIH_ANAPLMolecular cloning and expression analysis of ferritin, heavy polypeptide 1 gene from duck (Anas platyrhynchos).Xu Q.Chen Y.Zhang Y.Tong Y.Y.Huang Z.Y.Zhao W.M.Duan X.J.Li X.Chang G.B.Chen G.H.doi:10.1007/s11033-014-3503-02014Mol. Biol. Rep.416233-6240NUCLEOTIDE SEQUENCE [MRNA]TISSUE SPECIFICITYINDUCTIONThe protein of M(r) 21,000 constituting the prosome-like particle of duck erythroblasts is homologous to apoferritin.Coux O.Camoin L.Nothwang H.-G.Bey F.Silva-Pereira I.Keith G.Strosberg A.-D.Scherrer K.doi:10.1111/j.1432-1033.1992.tb17113.x1992Eur. J. Biochem.207823-832PROTEIN SEQUENCE OF 109-118 AND 159-181TISSUE SPECIFICITYErythroblastEuk_FerritinFerritinFerritin-likeFerritin-like_diironFerritin-like_SFFerritin_CSFerritin_DPS_domFERRITINFERRITIN HEAVY CHAINFerritinFerritin-likeAA sequenceFerritin heavy chainFerritin H subunit1.16.3.1Prosome-like particlePLPRNP particleFTH1Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.Inhibits translation of various mRNA species in vitro. Associates with a 35S prosome-like particle that contains non-translated mRNAs in a complex with proteins. May be involved in pre-translational regulation of some mRNA.Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.Expressed in erythroblasts (at protein level) (PubMed:1499559). Expressed in heart, liver, spleen, lung, kidney, large intestine, small intestine, muscle, glandular stomach, ovary and oviduct (PubMed:24981929).By duck hepatitis virus type I (DHV-1) (PubMed:24981929). By polyinosinic:polycytidylic acid (poly I:C) which mimicks viral double-stranded RNA (PubMed:1499559).Belongs to the ferritin family.Ferritin heavy chain212321181Ferritin-like diiron10159276265107141N180122023-06-28221232932bcf391f0090f37ceddd866787b968MATPLSQVRQNYHQDCEAAVNRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWENGLTAMECALHLEKNVNQSLLELHKLATEKNDPHLCDFIETHYLDEQVKAIKELGDHVTNLRKMGAPKYGMAEYLFDKHTLGHSDEStruetruetruetruetruetruetruetruetrue