Reviewed, UniProtKB/Swiss-Prot P80143 (UDDP_SULAC)

Names and origin

Protein names

Recommended name:
    Undecaprenyl-diphosphatase
    EC=3.6.1.27
Alternative name(s):
    Dolicholpyrophosphatase

Gene names

Name:	sepP
Ordered Locus Names:	Saci_1025

Organism

Sulfolobus acidocaldarius [Complete proteome] [HAMAP]

Taxonomic identifier

2285 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Induction	By polar lipids.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Molecular function	Hydrolase
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	undecaprenyl-diphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Undecaprenyl-diphosphatase		PRO_0000065717
Regions
	Transmembrane	5 – 25	21	Potential
	Transmembrane	53 – 73	21	Potential
	Transmembrane	79 – 99	21	Potential
	Transmembrane	138 – 158	21	Potential
	Transmembrane	164 – 184	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P80143-1 [UniParc]. Last modified August 30, 2005. Version 2. Checksum: 02E314C4DCDC9340	FASTA	206	23,525
	10 20 30 40 50 60 MRKYYYWILL LLFLILSIYI KLIGGEQNIG FNVELFKLIN YNQIATLNGL MVFLSKYGRE 70 80 90 100 110 120 YVWIPVTALL LIFKRTRKIG ITLVISFVIA IVLGEVSKYV MAQLRPFNFV NPTYLLEPKP 130 140 150 160 170 180 TDYSYPSGHA LIVSTGAVTL LLTSPKWMWI LGIIEAVLVS YSRVYVGVHW PLDVIAGWLL 190 200 GSWISFLSVQ IESTGPIKKI EQMLKA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The exo-ppase gene of the hyperthermophilic and acidophilic crenarchaeon Sulfolobus acidocaldarius." Schafer G., Moll R.G. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.
[2]	"The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota." Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E., Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A. J. Bacteriol. 187:4992-4999(2005) [PubMed: 15995215] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.
[3]	"Characterization and purification of a membrane-bound archaebacterial pyrophosphatase from Sulfolobus acidocaldarius." Meyer W., Schaefer G. Eur. J. Biochem. 207:741-746(1992) [PubMed: 1321720] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-30. Strain: ATCC 33909 / DSM 639 / IFO 15157 / JCM 8929 / NCIB 11770.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ550389 Genomic DNA. Translation: CAD79428.1. CP000077 Genomic DNA. Translation: AAY80382.1.
PIR	S24152.
RefSeq	YP_255675.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3472983.
GenomeReviews	Gene locus Saci_1025 in contig CP000077_GR.
KEGG	sai:Saci_1025.
NMPDR	fig|330779.3.peg.1333.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P80143.
OMA	SKYGREY.
Enzyme and pathway databases
BioCyc	SACI330779:SACI_1025-MON.
BRENDA	3.6.1.27. 434.
Family and domain databases
InterPro	IPR016118. P_Acid_Pase/Cl_peroxidase_N. IPR000326. P_Acid_Pase_2/haloperoxidase. [Graphical view]
Gene3D	G3DSA:1.20.144.10. P_Acid_Pase/Cl_peroxidase_N. 1 hit.
Pfam	PF01569. PAP2. 1 hit. [Graphical view]
SMART	SM00014. acidPPc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UDDP_SULAC

Accession

Primary (citable) accession number: P80143
Secondary accession number(s): Q4J9Z3, Q70SU5

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 30, 2005
Last modified:	November 3, 2009
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)