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P80029

- CRC1_HOMGA

UniProt

P80029 - CRC1_HOMGA

Protein

Crustacyanin-C1 subunit

Gene
N/A
Organism
Homarus gammarus (European lobster) (Homarus vulgaris)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.

    GO - Molecular functioni

    1. pigment binding Source: UniProtKB-KW
    2. small molecule binding Source: InterPro

    GO - Biological processi

    1. transport Source: UniProtKB-KW

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    Pigment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Crustacyanin-C1 subunit
    OrganismiHomarus gammarus (European lobster) (Homarus vulgaris)
    Taxonomic identifieri6707 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaNephropoideaNephropidaeHomarus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 181181Crustacyanin-C1 subunitPRO_0000201011Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi12 ↔ 121
    Disulfide bondi51 ↔ 173
    Disulfide bondi117 ↔ 150

    Keywords - PTMi

    Disulfide bond

    Expressioni

    Tissue specificityi

    Found in the carapace.

    Interactioni

    Subunit structurei

    Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2.

    Structurei

    Secondary structure

    1
    181
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi7 – 104
    Helixi17 – 248
    Helixi25 – 273
    Helixi28 – 314
    Beta strandi33 – 419
    Beta strandi48 – 5811
    Beta strandi63 – 719
    Beta strandi76 – 8510
    Beta strandi91 – 977
    Beta strandi102 – 1109
    Beta strandi112 – 12312
    Beta strandi127 – 14115
    Helixi144 – 15613
    Helixi161 – 1633
    Beta strandi164 – 1663
    Helixi175 – 1784

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1H91X-ray1.40A/B2-180[»]
    1I4UX-ray1.15A/B1-181[»]
    1OBQX-ray1.85A/B1-181[»]
    1OBUX-ray2.00A/B1-181[»]
    1S2PX-ray1.30A/B1-181[»]
    4ALOX-ray2.37A/B1-180[»]
    ProteinModelPortaliP80029.
    SMRiP80029. Positions 1-181.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP80029.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the calycin superfamily. Lipocalin family.Curated

    Family and domain databases

    Gene3Di2.40.128.20. 1 hit.
    InterProiIPR012674. Calycin.
    IPR011038. Calycin-like.
    IPR003057. Invtbrt_color.
    IPR002345. Lipocalin.
    IPR022271. Lipocalin_ApoD.
    IPR000566. Lipocln_cytosolic_FA-bd_dom.
    [Graphical view]
    PfamiPF00061. Lipocalin. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
    PRINTSiPR01273. INVTBRTCOLOR.
    PR00179. LIPOCALIN.
    SUPFAMiSSF50814. SSF50814. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P80029-1 [UniParc]FASTAAdd to Basket

    « Hide

    DKIPDFVVPG KCASVDRNKL WAEQTPNRNS YAGVWYQFAL TNNPYQLIEK    50
    CVRNEYSFDG KQFVIKSTGI AYDGNLLKRN GKLYPNPFGE PHLSIDYENS 100
    FAAPLVILET DYSNYACLYS CIDYNFGYHS DFSFIFSRSA NLADQYVKKC 150
    EAAFKNINVD TTRFVKTVQG SSCPYDTQKT L 181
    Length:181
    Mass (Da):20,667
    Last modified:August 1, 1991 - v1
    Checksum:i6A05C7CBA3498EE8
    GO

    Sequence databases

    PIRiS19534.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    Squeeze me - Issue 26 of September 2002

    Sequence databases

    PIRi S19534.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1H91 X-ray 1.40 A/B 2-180 [» ]
    1I4U X-ray 1.15 A/B 1-181 [» ]
    1OBQ X-ray 1.85 A/B 1-181 [» ]
    1OBU X-ray 2.00 A/B 1-181 [» ]
    1S2P X-ray 1.30 A/B 1-181 [» ]
    4ALO X-ray 2.37 A/B 1-180 [» ]
    ProteinModelPortali P80029.
    SMRi P80029. Positions 1-181.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P80029.

    Family and domain databases

    Gene3Di 2.40.128.20. 1 hit.
    InterProi IPR012674. Calycin.
    IPR011038. Calycin-like.
    IPR003057. Invtbrt_color.
    IPR002345. Lipocalin.
    IPR022271. Lipocalin_ApoD.
    IPR000566. Lipocln_cytosolic_FA-bd_dom.
    [Graphical view ]
    Pfami PF00061. Lipocalin. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036893. Lipocalin_ApoD. 1 hit.
    PRINTSi PR01273. INVTBRTCOLOR.
    PR00179. LIPOCALIN.
    SUPFAMi SSF50814. SSF50814. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence and model for the C1 subunit of the carotenoprotein, crustacyanin, and model for the dimer, beta-crustacyanin, formed from the C1 and A2 subunits with astaxanthin."
      Keen J.N., Caceres I., Eliopoulos E.E., Zagalsky P.F., Findlay J.B.C.
      Eur. J. Biochem. 202:31-40(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
    2. "The C1 subunit of alpha-crustacyanin: the de novo phasing of the crystal structure of a 40 kDa homodimeric protein using the anomalous scattering from S atoms combined with direct methods."
      Gordon E.J., Leonard G.A., McSweeney S., Zagalsky P.F.
      Acta Crystallogr. D 57:1230-1237(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF HOMODIMER.

    Entry informationi

    Entry nameiCRC1_HOMGA
    AccessioniPrimary (citable) accession number: P80029
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1991
    Last sequence update: August 1, 1991
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3