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P80029

- CRC1_HOMGA

UniProt

P80029 - CRC1_HOMGA

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Protein

Crustacyanin-C1 subunit

Gene
N/A
Organism
Homarus gammarus (European lobster) (Homarus vulgaris)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.

GO - Molecular functioni

  1. pigment binding Source: UniProtKB-KW
  2. small molecule binding Source: InterPro

GO - Biological processi

  1. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Pigment

Names & Taxonomyi

Protein namesi
Recommended name:
Crustacyanin-C1 subunit
OrganismiHomarus gammarus (European lobster) (Homarus vulgaris)
Taxonomic identifieri6707 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaNephropoideaNephropidaeHomarus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181Crustacyanin-C1 subunitPRO_0000201011Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi12 ↔ 121
Disulfide bondi51 ↔ 173
Disulfide bondi117 ↔ 150

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Found in the carapace.

Interactioni

Subunit structurei

Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2.

Structurei

Secondary structure

1
181
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 104
Helixi17 – 248
Helixi25 – 273
Helixi28 – 314
Beta strandi33 – 419
Beta strandi48 – 5811
Beta strandi63 – 719
Beta strandi76 – 8510
Beta strandi91 – 977
Beta strandi102 – 1109
Beta strandi112 – 12312
Beta strandi127 – 14115
Helixi144 – 15613
Helixi161 – 1633
Beta strandi164 – 1663
Helixi175 – 1784

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1H91X-ray1.40A/B2-180[»]
1I4UX-ray1.15A/B1-181[»]
1OBQX-ray1.85A/B1-181[»]
1OBUX-ray2.00A/B1-181[»]
1S2PX-ray1.30A/B1-181[»]
4ALOX-ray2.37A/B1-180[»]
ProteinModelPortaliP80029.
SMRiP80029. Positions 1-181.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP80029.

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSiPR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

P80029-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
DKIPDFVVPG KCASVDRNKL WAEQTPNRNS YAGVWYQFAL TNNPYQLIEK
60 70 80 90 100
CVRNEYSFDG KQFVIKSTGI AYDGNLLKRN GKLYPNPFGE PHLSIDYENS
110 120 130 140 150
FAAPLVILET DYSNYACLYS CIDYNFGYHS DFSFIFSRSA NLADQYVKKC
160 170 180
EAAFKNINVD TTRFVKTVQG SSCPYDTQKT L
Length:181
Mass (Da):20,667
Last modified:August 1, 1991 - v1
Checksum:i6A05C7CBA3498EE8
GO

Sequence databases

PIRiS19534.

Cross-referencesi

Web resourcesi

Protein Spotlight

Squeeze me - Issue 26 of September 2002

Sequence databases

PIRi S19534.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1H91 X-ray 1.40 A/B 2-180 [» ]
1I4U X-ray 1.15 A/B 1-181 [» ]
1OBQ X-ray 1.85 A/B 1-181 [» ]
1OBU X-ray 2.00 A/B 1-181 [» ]
1S2P X-ray 1.30 A/B 1-181 [» ]
4ALO X-ray 2.37 A/B 1-180 [» ]
ProteinModelPortali P80029.
SMRi P80029. Positions 1-181.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P80029.

Family and domain databases

Gene3Di 2.40.128.20. 1 hit.
InterProi IPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view ]
Pfami PF00061. Lipocalin. 1 hit.
[Graphical view ]
PIRSFi PIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSi PR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMi SSF50814. SSF50814. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence and model for the C1 subunit of the carotenoprotein, crustacyanin, and model for the dimer, beta-crustacyanin, formed from the C1 and A2 subunits with astaxanthin."
    Keen J.N., Caceres I., Eliopoulos E.E., Zagalsky P.F., Findlay J.B.C.
    Eur. J. Biochem. 202:31-40(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. "The C1 subunit of alpha-crustacyanin: the de novo phasing of the crystal structure of a 40 kDa homodimeric protein using the anomalous scattering from S atoms combined with direct methods."
    Gordon E.J., Leonard G.A., McSweeney S., Zagalsky P.F.
    Acta Crystallogr. D 57:1230-1237(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF HOMODIMER.

Entry informationi

Entry nameiCRC1_HOMGA
AccessioniPrimary (citable) accession number: P80029
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3