SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P80007

- CRA2_HOMGA

UniProt

P80007 - CRA2_HOMGA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Crustacyanin-A2 subunit

Gene
N/A
Organism
Homarus gammarus (European lobster) (Homarus vulgaris)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Binds the carotenoid astaxanthin (AXT) which provides the blue coloration to the carapace of the lobster.

GO - Molecular functioni

  1. pigment binding Source: UniProtKB-KW
  2. small molecule binding Source: InterPro

GO - Biological processi

  1. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Pigment

Names & Taxonomyi

Protein namesi
Recommended name:
Crustacyanin-A2 subunit
OrganismiHomarus gammarus (European lobster) (Homarus vulgaris)
Taxonomic identifieri6707 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaNephropoideaNephropidaeHomarus

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 174174Crustacyanin-A2 subunitPRO_0000201010Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi12 ↔ 1191 Publication
Disulfide bondi46 ↔ 1701 Publication

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Found in the carapace.

Interactioni

Subunit structurei

Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2.

Protein-protein interaction databases

MINTiMINT-242150.

Structurei

Secondary structure

1
174
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 104
Turni23 – 264
Beta strandi28 – 358
Beta strandi45 – 5410
Turni55 – 584
Beta strandi59 – 679
Beta strandi69 – 713
Beta strandi73 – 764
Beta strandi79 – 813
Beta strandi90 – 945
Beta strandi96 – 983
Beta strandi101 – 1088
Beta strandi110 – 12112
Beta strandi123 – 13614
Beta strandi139 – 1413
Helixi142 – 15413
Helixi158 – 1603

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1GKAX-ray3.23B1-174[»]
ProteinModelPortaliP80007.
SMRiP80007. Positions 1-174.

Miscellaneous databases

EvolutionaryTraceiP80007.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR022272. Lipocalin_CS.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PIRSFiPIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSiPR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00213. LIPOCALIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P80007-1 [UniParc]FASTAAdd to Basket

« Hide

DGIPSFVTAG KCASVANQDN FDLRRYAGRW YQTHIIENAY QPVTRCIHSN    50
YEYSTNDYGF KVTTAGFNPN DEYLKIDFKV YPTKEFPAAH MLIDAPSVFA 100
APYEVIETDY ETYSCVYSCI TTDNYKSEFA FVFSRTPQTS GPAVEKTAAV 150
FNKNGVEFSK FVPVSHTAEC VYRA 174
Length:174
Mass (Da):19,670
Last modified:May 1, 1991 - v1
Checksum:iAC47FAA650C5E44E
GO

Sequence databases

PIRiS15391.

Cross-referencesi

Web resourcesi

Protein Spotlight

Squeeze me - Issue 26 of September 2002

Sequence databases

PIRi S15391.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1GKA X-ray 3.23 B 1-174 [» ]
ProteinModelPortali P80007.
SMRi P80007. Positions 1-174.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-242150.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P80007.

Family and domain databases

Gene3Di 2.40.128.20. 1 hit.
InterProi IPR012674. Calycin.
IPR011038. Calycin-like.
IPR003057. Invtbrt_color.
IPR002345. Lipocalin.
IPR022271. Lipocalin_ApoD.
IPR022272. Lipocalin_CS.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view ]
Pfami PF00061. Lipocalin. 1 hit.
[Graphical view ]
PIRSFi PIRSF036893. Lipocalin_ApoD. 1 hit.
PRINTSi PR01273. INVTBRTCOLOR.
PR00179. LIPOCALIN.
SUPFAMi SSF50814. SSF50814. 1 hit.
PROSITEi PS00213. LIPOCALIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence and model for the A2 subunit of the carotenoid pigment complex, crustacyanin."
    Keen J.N., Caceres I., Eliopoulos E.E., Zagalsky P.F., Findlay J.B.C.
    Eur. J. Biochem. 197:407-417(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. "The molecular basis of the coloration mechanism in lobster shell: beta-crustacyanin at 3.2-A resolution."
    Cianci M., Rizkallah P.J., Olczak A., Raftery J., Chayen N.E., Zagalsky P.F., Helliwell J.R.
    Proc. Natl. Acad. Sci. U.S.A. 99:9795-9800(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.23 ANGSTROMS) OF HETERODIMER OF A1 AND A3 IN COMPLEX WITH ASTAXANTHIN, DISULFIDE BONDS.

Entry informationi

Entry nameiCRA2_HOMGA
AccessioniPrimary (citable) accession number: P80007
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: February 19, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi