Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S4

Gene

RPS4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-BTA-72649. Translation initiation complex formation.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-BTA-72702. Ribosomal scanning and start codon recognition.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:RPS4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308201 – 26340S ribosomal protein S4Add BLAST263

Proteomic databases

PaxDbiP79103.
PeptideAtlasiP79103.
PRIDEiP79103.

Expressioni

Gene expression databases

BgeeiENSBTAG00000018800.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000025024.

Structurei

3D structure databases

ProteinModelPortaliP79103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 104S4 RNA-bindingAdd BLAST63

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
GeneTreeiENSGT00390000005569.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiP79103.
KOiK02987.
OMAiRKDYKFP.
OrthoDBiEOG091G0MYF.
TreeFamiTF300612.

Family and domain databases

Gene3Di3.10.290.10. 2 hits.
HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiView protein in InterPro
IPR032277. 40S_S4_C.
IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiView protein in Pfam
PF16121. 40S_S4_C. 1 hit.
PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667. Ribosomal_S4e_central. 1 hit.
SMARTiView protein in SMART
SM00363. S4. 1 hit.
PROSITEiView protein in PROSITE
PS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.

Sequencei

Sequence statusi: Complete.

P79103-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR
110 120 130 140 150
LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,598
Last modified:January 23, 2007 - v3
Checksum:i87200E545A8958B0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80I → V in BAA21078 (PubMed:8808278).Curated1
Sequence conflicti95T → I in BAA21078 (PubMed:8808278).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102476 mRNA. Translation: AAI02477.1.
BC141995 mRNA. Translation: AAI41996.1.
D50107 mRNA. Translation: BAA21078.1.
RefSeqiNP_001030522.1. NM_001035445.2.
UniGeneiBt.54084.
Bt.65280.

Genome annotation databases

EnsembliENSBTAT00000025024; ENSBTAP00000025024; ENSBTAG00000018800.
GeneIDi614241.
KEGGibta:614241.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRS4_BOVIN
AccessioniPrimary (citable) accession number: P79103
Secondary accession number(s): A5PJ76, Q3T0A5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: July 5, 2017
This is version 112 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families