Reviewed, UniProtKB/Swiss-Prot P79085 (ALTA1_ALTAL)

Names and origin

Protein names

Recommended name:
    Major allergen Alt a 1
Alternative name(s):
    Allergen=Alt a 1

Gene names

Name:

ALTA1

Organism

Alternaria alternata (Alternaria rot fungus)

Taxonomic identifier

5599 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporaceae › mitosporic Pleosporaceae › Alternaria › Alternaria alternata group

Protein attributes

Sequence length	157 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subunit structure	Homodimer; disulfide-linked.
Subcellular location	Secreted.
Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the ALTA1 family.

Ontologies

Keywords
Cellular component	Secreted
Disease	Allergen
Domain	Signal
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18
	Chain	19 – 157	139	Major allergen Alt a 1		PRO_0000020699

Sequences

	Sequence		Length	Mass (Da)
	P79085-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: AAC20D0819198246	FASTA	157	16,980
	10 20 30 40 50 60 MQFTTIASLF AAAGLAAAAP LESRQDTASC PVTTEGDYVW KISEFYGRKP EGTYYNSLGF 70 80 90 100 110 120 NIKATNGGTL DFTCSAQADK LEDHKWYSCG ENSFMDFSFD SDRSGLLLKQ KVSDDITYVA 130 140 150 TATLPNYCRA GGNGPKDFVC QGVADAYITL VTLPKSS

References

[1]	"Isolation and expression of a cDNA clone encoding an Alternaria alternata Alt a 1 subunit." De Vouge M.W., Thaker A.J., Curran I.H., Zhang L., Muradia G., Rode H., Vijay H.M. Int. Arch. Allergy Immunol. 111:385-395(1996) [PubMed: 8957113] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
[2]	Unger A.M., Lechenauer E., Simon B., Oberkofler H., Probst G., Achatz G., Breitenbach M. Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: 08-0203-Berlin.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U86752 mRNA. Translation: AAB47552.1. U82633 mRNA. Translation: AAB40400.1.
3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALTA1_ALTAL

Accession

Primary (citable) accession number: P79085

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2001
Last sequence update:	May 1, 1997
Last modified:	June 16, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)