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Protein
Submitted name:

Delta-9 fatty acid desaturase

Gene

Ole 1

Organism
Cutaneotrichosporon curvatus (Oleaginous yeast) (Cryptococcus curvatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Fe2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Fatty acid biosynthesisUniRule annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

HemeSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Delta-9 fatty acid desaturaseImported (EC:1.14.99.5Imported)
Gene namesi
Name:Ole 1Imported
OrganismiCutaneotrichosporon curvatus (Oleaginous yeast) (Cryptococcus curvatus)Imported
Taxonomic identifieri57679 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTrichosporonalesTrichosporonaceaeCutaneotrichosporon

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei60 – 8223HelicalSequence analysisAdd
BLAST
Transmembranei89 – 11022HelicalSequence analysisAdd
BLAST
Transmembranei202 – 22322HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliP79078.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini340 – 43293Cytochrome b5 heme-bindingInterPro annotationAdd
BLAST

Domaini

The histidine box domains are involved in binding the catalytic metal ions.UniRule annotation

Sequence similaritiesi

Belongs to the fatty acid desaturase type 1 family.UniRule annotation
Contains cytochrome b5 heme-binding domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di3.10.120.10. 1 hit.
InterProiIPR009160. Acyl-CoA_deSatase_haem/ster-bd.
IPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
IPR015876. Fatty_acid_desaturase-1_core.
IPR005804. Fatty_acid_desaturase_dom.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
PF00487. FA_desaturase. 1 hit.
[Graphical view]
PIRSFiPIRSF000345. OLE1. 1 hit.
PRINTSiPR00363. CYTOCHROMEB5.
PR00075. FACDDSATRASE.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P79078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASTKQAST TVAQPSGKPV TNVIDPERDD FIVPDNYVTR TVENMKMLPP
60 70 80 90 100
VTWRNLHKNI QWISFLALTI PPAMAIYGLC TVPVQTKTFI WSVVYYFITG
110 120 130 140 150
LGITAGYHRL WAHRSYNASK PLQYFLALCG AGSVQGSIRW WSRGHRAHHR
160 170 180 190 200
YTDTKLDPYS AHEGFWHAHM GWMLIKPRGK IGVADISDLS KNPVVKWQHN
210 220 230 240 250
NYVALLFFMG LAFPTLVAGL GWGDWWGGLF FAGAARLVFV HHSTFCVNSL
260 270 280 290 300
AHWLGETPFD NKHTPKDHFI TALVTVGEGY HNFHHQFPMD FRNAIKWYQY
310 320 330 340 350
DPTKWFIWTM AQLGLASHLK KFPDNEIKKG QYTMKLMQLQ EQSEKLEWPK
360 370 380 390 400
HSNDLPVISW EDFQAESKTR ALIAVHGFIH DCSSFIEDHP GGAHLIKRAI
410 420 430 440 450
GTDSTTAFFG GVYDHSNAAH NLLAMMRVGV LDGGMEVEHL KVGRLTRSNS
460 470 480 490 500
ADSLVSDAPS SASSTVSASS ILSEVEDMDK PERKPSTSRS PRCPTPGRSP
510 520 530 540 550
CLLRRSIASS ARPPRSAQDS SRASRAPPRP ASHGQRALTL LSRLRAFSVE

HPGFH
Length:555
Mass (Da):62,221
Last modified:May 1, 1997 - v1
Checksum:iC664CC352451BCF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10421 Genomic DNA. Translation: CAA71448.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10421 Genomic DNA. Translation: CAA71448.1.

3D structure databases

ProteinModelPortaliP79078.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.10.120.10. 1 hit.
InterProiIPR009160. Acyl-CoA_deSatase_haem/ster-bd.
IPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
IPR015876. Fatty_acid_desaturase-1_core.
IPR005804. Fatty_acid_desaturase_dom.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
PF00487. FA_desaturase. 1 hit.
[Graphical view]
PIRSFiPIRSF000345. OLE1. 1 hit.
PRINTSiPR00363. CYTOCHROMEB5.
PR00075. FACDDSATRASE.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and expression of the delta 9 fatty acid desaturase gene from Cryptococcus curvatus ATCC 20509 containing histidine boxes and a cytochrome b5 domain."
    Meesters P.A., Springer J., Eggink G.
    Appl. Microbiol. Biotechnol. 47:663-667(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 20509Imported.

Entry informationi

Entry nameiP79078_CUTCU
AccessioniPrimary (citable) accession number: P79078
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: July 6, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.