P79021 (AXHA_ASPTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha-L-arabinofuranosidase axhA
EC=3.2.1.55

Alternative name(s):
Arabinoxylan arabinofuranohydrolase axhA

Gene names

Name:

axhA

Organism

Aspergillus tubingensis

Taxonomic identifier

5068 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan By similarity.
Catalytic activity	Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Subcellular location	Secreted Ref.1.
Sequence similarities	Belongs to the glycosyl hydrolase 62 family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	L-arabinose metabolic process Inferred from electronic annotation. Source: InterPro xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alpha-N-arabinofuranosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential
	Chain	27 – 332	306	Probable alpha-L-arabinofuranosidase axhA		PRO_0000008035
Amino acid modifications
	Glycosylation	313	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P79021 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 409FA65D4686C143	FASTA	332	36,050
	10 20 30 40 50 60 MKFFKAKGSL LSSGIYLIAL TPFVNAKCAL PSSYSWSSTD ALATPKSGWT ALKDFTDVVS 70 80 90 100 110 120 DGKHIVYAST TDEAGNYGSM TFGAFSEWSN MASASQTATP FNAVAPTLFY FKPKSIWVLA 130 140 150 160 170 180 YQWGSSTFTY RTSQDPTNVN GWSSEQALFT GKISDSSTNA IDQTVIGDDT NMYLFFAGDN 190 200 210 220 230 240 GKIYRSSMSI NDFPGSFGSQ YEVILSGARN DLFEAVQVYT VDGGEGDTKY LMIVEAIGST 250 260 270 280 290 300 GHRYFRSFTA SSLGGEWTAQ AASEDQPFAG KANSGATWTE DISHGDLVRN NPDQTMTVDP 310 320 330 CNLQLLYQGH DPNSSGDYNL LPWKPGVLTL KQ

References

[1]

"Arabinoxylan degradation by fungi: characterization of the arabinoxylan-arabinofuranohydrolase encoding genes from Aspergillus niger and Aspergillus tubingensis." Gielkens M.M.C., Visser J., de Graaff L.H. Curr. Genet. 31:22-29(1997) [PubMed: 9000377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 27-34 AND 233-245, SUBCELLULAR LOCATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z78010 Genomic DNA. Translation: CAB01408.1.
3D structure databases
ProteinModelPortal	P79021.
ModBase	Search...
Protein family/group databases
CAZy	GH62. Glycoside Hydrolase Family 62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR005193. GH62_arabinosidase. IPR023296. Glyco_hydro_43_beta-prop. [Graphical view]
Gene3D	G3DSA:2.115.10.20. Glyco_hydro_43_beta-prop. 1 hit.
Pfam	PF03664. Glyco_hydro_62. 1 hit. [Graphical view]
SUPFAM	SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
ProtoNet	Search...

Entry information

Entry name

AXHA_ASPTU

Accession

Primary (citable) accession number: P79021

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	May 1, 1997
Last modified:	May 31, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program