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P79019

- AXHA_ASPNG

UniProt

P79019 - AXHA_ASPNG

Protein

Alpha-L-arabinofuranosidase axhA

Gene

axhA

Organism
Aspergillus niger
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 May 1997)
      Previous versions | rss
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    Functioni

    Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan.

    Catalytic activityi

    Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.

    GO - Molecular functioni

    1. alpha-L-arabinofuranosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. L-arabinose metabolic process Source: InterPro
    2. xylan catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

    Protein family/group databases

    CAZyiGH62. Glycoside Hydrolase Family 62.
    mycoCLAPiAXH62A_ASPNG.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alpha-L-arabinofuranosidase axhA (EC:3.2.1.55)
    Alternative name(s):
    Arabinoxylan arabinofuranohydrolase axhA
    Gene namesi
    Name:axhA
    OrganismiAspergillus niger
    Taxonomic identifieri5061 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

    Subcellular locationi

    Secreted 1 Publication

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 332306Alpha-L-arabinofuranosidase axhAPRO_0000008034Add
    BLAST

    Expressioni

    Inductioni

    Mainly expressed when grown on xylan and much less on L-arabitol, L-arabinose and D-xylose. Expression is under the control of the carbon catabolite repressor creA.1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliP79019.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 62 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG81570.

    Family and domain databases

    InterProiIPR005193. GH62_arabinosidase.
    IPR023296. Glyco_hydro_beta-prop.
    [Graphical view]
    PfamiPF03664. Glyco_hydro_62. 1 hit.
    [Graphical view]
    SUPFAMiSSF75005. SSF75005. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P79019-1 [UniParc]FASTAAdd to Basket

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    MKFLKAKGSL LSSGIYLIAL APFVNAKCAL PSTYSWTSTD ALATPKSGWT    50
    ALKDFTDVVS NGKHIVYAST TDTQGNYGSM GFGAFSDWSD MASASQTATS 100
    FSAVAPTLFY FQPKSIWVLA YQWGSSTFTY RTSQDPTNVN GWSSEQALFT 150
    GKISGSSTGA IDQTVIGDDT NMYLFFAGDN GKIYRSSMSI NDFPGSFGSQ 200
    YEEILSGATN DLFEAVQVYT VDGGEGDSKY LMIVEAIGST GHRYFRSFTA 250
    SSLGGEWTAQ AASEDQPFAG KANSGATWTD DISHGDLVRN NPDQTMTVDP 300
    CNLQLLYQGH DPNSNSDYNL LPWKPGVLTL KQ 332
    Length:332
    Mass (Da):35,837
    Last modified:May 1, 1997 - v1
    Checksum:iF6EEE44EB8C43FEB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z78011 Genomic DNA. Translation: CAB01409.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z78011 Genomic DNA. Translation: CAB01409.1 .

    3D structure databases

    ProteinModelPortali P79019.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH62. Glycoside Hydrolase Family 62.
    mycoCLAPi AXH62A_ASPNG.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG81570.

    Family and domain databases

    InterProi IPR005193. GH62_arabinosidase.
    IPR023296. Glyco_hydro_beta-prop.
    [Graphical view ]
    Pfami PF03664. Glyco_hydro_62. 1 hit.
    [Graphical view ]
    SUPFAMi SSF75005. SSF75005. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Arabinoxylan degradation by fungi: characterization of the arabinoxylan-arabinofuranohydrolase encoding genes from Aspergillus niger and Aspergillus tubingensis."
      Gielkens M.M.C., Visser J., de Graaff L.H.
      Curr. Genet. 31:22-29(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, INDUCTION.
      Strain: ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400.

    Entry informationi

    Entry nameiAXHA_ASPNG
    AccessioniPrimary (citable) accession number: P79019
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: May 1, 1997
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3