P78983 (HSP70_ALTAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Heat shock 70 kDa protein

Alternative name(s):
Allergen=Alt a 3

Gene names

Name:	HSP70
Synonyms:	ALTA3

Organism

Alternaria alternata (Alternaria rot fungus) (Torula alternata)

Taxonomic identifier

5599 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › dothideomyceta › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Pleosporaceae › mitosporic Pleosporaceae › Alternaria › Alternaria alternata group

Protein attributes

Sequence length	152 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Allergenic properties	Causes an allergic reaction in human.
Sequence similarities	Belongs to the heat shock protein 70 family.

Ontologies

Keywords
Biological process	Stress response
Disease	Allergen
Ligand	ATP-binding Nucleotide-binding
Molecular function	Chaperone
Gene Ontology (GO)
Biological_process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 152	›152	Heat shock 70 kDa protein		PRO_0000078360
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P78983 [UniParc]. Last modified June 20, 2001. Version 2. Checksum: 87442B9F45385E6A	FASTA	152	16,233
	10 20 30 40 50 60 KTNKIVITND KGRLSKEEIE RMLAEAEKYK AEDEAEAARI SAKNALESYA YSLRNTLSDS 70 80 90 100 110 120 KVDEKLDAGD KQKLTAEIDK TVQWLDDNQT ATKDEYESQQ KELEGVANPI MMKFYGAGGE 130 140 150 GGMPGGMPGG GMPGGAPGGA AGDDGPTVEE VD

References

[1]

"Molecular cloning of IgE-binding fragments of Alternaria alternata allergens." De Vouge M.W., Thaker A.J., Zhang L., Muradia G., Rode H., Vijay H.M. Int. Arch. Allergy Immunol. 116:261-268(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], CROSS-REACTIVITY WITH ATOPIC HUMAN SERA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U87807 mRNA. Translation: AAB48042.1. U87808 mRNA. Translation: AAB48043.1.
3D structure databases
ProteinModelPortal	P78983.
SMR	P78983. Positions 1-57.
ModBase	Search...
Protein family/group databases
Allergome	17. Alt a 3. 3059. Alt a 3.0101.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR013126. Hsp_70_fam. [Graphical view]
Pfam	PF00012. HSP70. 1 hit. [Graphical view]
PROSITE	PS00297. HSP70_1. Partial match. PS00329. HSP70_2. Partial match. PS01036. HSP70_3. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HSP70_ALTAL

Accession

Primary (citable) accession number: P78983
Secondary accession number(s): P78984

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2001
Last sequence update:	June 20, 2001
Last modified:	February 6, 2013
This is version 57 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program