P78817 (YFE6_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized alpha-1,2-galactosyltransferase C637.06
EC=2.4.1.-

Gene names

ORF Names:

SPAC637.06

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Endoplasmic reticulum membrane; Single-pass type II membrane protein By similarity.
Sequence similarities	Belongs to the glycosyltransferase 34 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fungal-type cell wall biogenesis Inferred from sequence or structural similarity. Source: GeneDB_Spombe protein galactosylation Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Cellular component	Golgi membrane Inferred from sequence or structural similarity. Source: GeneDB_Spombe endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alpha-1,2-galactosyltransferase activity Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Uncharacterized alpha-1,2-galactosyltransferase C637.06		PRO_0000339341
Regions
	Topological domain	1 – 44	44	Cytoplasmic Potential
	Transmembrane	45 – 62	18	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	63 – 347	285	Lumenal Potential
Experimental info
	Sequence conflict	5	1	K → T in BAA13828. Ref.1
	Sequence conflict	346	1	F → L in BAA13828. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P78817 [UniParc]. Last modified May 1, 2000. Version 2. Checksum: B9775DEAAF30B9E4	FASTA	347	41,127
	10 20 30 40 50 60 MWNPKKKSEA LAKFKSFPYP KPGTSNVLDS KEGDTRRKYF TKTHLHRLFV FVVLLLCSGY 70 80 90 100 110 120 FLKHTLLTRP KESNVVMIFV NNIGGGVLDV KSPRQWELEK ISTENKKKYA ERHGYHFFVK 130 140 150 160 170 180 STGLKRRYAH EWRESWEKAD YIMEAMKKYP HAEWFWWVDL TTFIMEPQYS LEKLIINRLD 190 200 210 220 230 240 HIATRNITDS MEFNPKNFHE IPFVDYSEDI NFILGQDCNG FSLGSFLVRR SDWTSRLMDF 250 260 270 280 290 300 LWDPVVYGQK HMDWPHDEQN AIEYFYENNA WLRSGMGFVP LRLFNSYPPG ACAGEGENPR 310 320 330 340 FFYNQKEGDF LVNLAGCNYG RDCLDEINHY KGLAQRKRGW RKLVPFL

References

[1]

"Identification of open reading frames in Schizosaccharomyces pombe cDNAs." Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H. DNA Res. 4:363-369(1997) [PubMed: 9501991] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: PR745.

[2]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D89166 mRNA. Translation: BAA13828.1. CU329670 Genomic DNA. Translation: CAA22585.1.
PIR	T38998. T42528.
RefSeq	NP_594624.1. NM_001020052.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P78817.
Protein family/group databases
CAZy	GT34. Glycosyltransferase Family 34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPAC637.06.1; SPAC637.06.1:pep; SPAC637.06.
GeneID	2543384.
KEGG	spo:SPAC637.06.
NMPDR	fig|4896.1.peg.4594.
Organism-specific databases
GeneDB_Spombe	SPAC637.06.
Phylogenomic databases
eggNOG	fuNOG05170.
GeneTree	EFGT00050000004280.
HOGENOM	HBG397221.
OMA	HEYREGW.
OrthoDB	EOG441TKR.
Gene expression databases
ArrayExpress	P78817.
Family and domain databases
InterPro	IPR008630. Glyco_trans_34. [Graphical view]
KO	K05531.
Pfam	PF05637. Glyco_transf_34. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YFE6_SCHPO

Accession

Primary (citable) accession number: P78817
Secondary accession number(s): Q1L849

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program