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Protein

Uncharacterized protein C1919.03c

Gene

SPCC1919.03c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-SPO-163680. AMPK inhibits chREBP transcriptional activation activity.
R-SPO-200425. Import of palmitoyl-CoA into the mitochondrial matrix.
R-SPO-380972. Energy dependent regulation of mTOR by LKB1-AMPK.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1919.03c
Gene namesi
ORF Names:SPCC1919.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1919.03c.
PomBaseiSPCC1919.03c.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nucleotide-activated protein kinase complex Source: PomBase
  • nucleus Source: PomBase
  • plasma membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Uncharacterized protein C1919.03cPRO_0000339125Add
BLAST

Proteomic databases

MaxQBiP78789.

PTM databases

SwissPalmiP78789.

Interactioni

Protein-protein interaction databases

BioGridi275702. 209 interactions.
DIPiDIP-29521N.
MINTiMINT-4691237.

Structurei

Secondary structure

1
298
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi209 – 2113Combined sources
Helixi214 – 2163Combined sources
Beta strandi217 – 2193Combined sources
Beta strandi220 – 2234Combined sources
Helixi234 – 2363Combined sources
Helixi240 – 2423Combined sources
Helixi247 – 2504Combined sources
Beta strandi251 – 2533Combined sources
Helixi259 – 2613Combined sources
Beta strandi266 – 2683Combined sources
Beta strandi271 – 28313Combined sources
Beta strandi286 – 2949Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OOXX-ray2.60B/D203-298[»]
2OOYX-ray2.88B/D203-298[»]
2QR1X-ray2.70B/D203-298[»]
2QRCX-ray2.70B/D203-298[»]
2QRDX-ray2.41B/D203-298[»]
2QREX-ray3.01B/D203-298[»]
ProteinModelPortaliP78789.
SMRiP78789. Positions 205-297.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP78789.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiP78789.
KOiK07199.
OMAiYACSIKD.
OrthoDBiEOG7BS4NQ.
PhylomeDBiP78789.

Family and domain databases

InterProiIPR032640. AMPK1_CBM.
IPR006828. ASC_dom.
IPR014756. Ig_E-set.
[Graphical view]
PfamiPF16561. AMPK1_CBM. 1 hit.
PF04739. AMPKBI. 1 hit.
[Graphical view]
SMARTiSM01010. AMPKBI. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

P78789-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNVQSQEGE TRAHAVPSQD ATTTPDNANN VPKEPRAQSM ISIAADDLNQ
60 70 80 90 100
EGEMSDDNQQ EGGNNRTSQN GTSGSSGHTK RRSQTSGKKT HQPYSGPCVP
110 120 130 140 150
TIIRWRGGGE VVYVTGSFSR WKKKIQLLKS EDYTVLLQLR PGTQRFKFLV
160 170 180 190 200
DGIWCCSSDF PTATDAEGNL YNYLEVEANE KLGASIDERL SQVHTDLPME
210 220 230 240 250
EKSESEQYST EIPAFLTSNT LQELKLPKPP SLPPHLEKCI LNSNTAYKED
260 270 280 290
QSVLPNPNHV LLNHLAAANT QLGVLALSAT TRYHRKYVTT AMFKNFDV
Length:298
Mass (Da):32,970
Last modified:May 1, 2000 - v2
Checksum:iB9D5A078C166E730
GO

Sequence cautioni

The sequence BAA13800.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89138 mRNA. Translation: BAA13800.1. Different initiation.
CU329672 Genomic DNA. Translation: CAA22634.1.
AB027823 Genomic DNA. Translation: BAA87127.1.
PIRiT41228.
T42415.
RefSeqiNP_588485.1. NM_001023476.2.

Genome annotation databases

EnsemblFungiiSPCC1919.03c.1; SPCC1919.03c.1:pep; SPCC1919.03c.
GeneIDi2539130.
KEGGispo:SPCC1919.03c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89138 mRNA. Translation: BAA13800.1. Different initiation.
CU329672 Genomic DNA. Translation: CAA22634.1.
AB027823 Genomic DNA. Translation: BAA87127.1.
PIRiT41228.
T42415.
RefSeqiNP_588485.1. NM_001023476.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OOXX-ray2.60B/D203-298[»]
2OOYX-ray2.88B/D203-298[»]
2QR1X-ray2.70B/D203-298[»]
2QRCX-ray2.70B/D203-298[»]
2QRDX-ray2.41B/D203-298[»]
2QREX-ray3.01B/D203-298[»]
ProteinModelPortaliP78789.
SMRiP78789. Positions 205-297.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275702. 209 interactions.
DIPiDIP-29521N.
MINTiMINT-4691237.

PTM databases

SwissPalmiP78789.

Proteomic databases

MaxQBiP78789.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1919.03c.1; SPCC1919.03c.1:pep; SPCC1919.03c.
GeneIDi2539130.
KEGGispo:SPCC1919.03c.

Organism-specific databases

EuPathDBiFungiDB:SPCC1919.03c.
PomBaseiSPCC1919.03c.

Phylogenomic databases

InParanoidiP78789.
KOiK07199.
OMAiYACSIKD.
OrthoDBiEOG7BS4NQ.
PhylomeDBiP78789.

Enzyme and pathway databases

ReactomeiR-SPO-163680. AMPK inhibits chREBP transcriptional activation activity.
R-SPO-200425. Import of palmitoyl-CoA into the mitochondrial matrix.
R-SPO-380972. Energy dependent regulation of mTOR by LKB1-AMPK.

Miscellaneous databases

EvolutionaryTraceiP78789.
PROiP78789.

Family and domain databases

InterProiIPR032640. AMPK1_CBM.
IPR006828. ASC_dom.
IPR014756. Ig_E-set.
[Graphical view]
PfamiPF16561. AMPK1_CBM. 1 hit.
PF04739. AMPKBI. 1 hit.
[Graphical view]
SMARTiSM01010. AMPKBI. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
    Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
    DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: PR745.
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  3. "Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
    Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
    Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 97-117.
    Strain: ATCC 38364 / 968.
  4. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYC63_SCHPO
AccessioniPrimary (citable) accession number: P78789
Secondary accession number(s): Q1L851, Q9UU43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: May 1, 2000
Last modified: June 8, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.