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Protein

Vesicle transport v-SNARE protein vti1

Gene

vti1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-SPO-6811440. Retrograde transport at the Trans-Golgi-Network.

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle transport v-SNARE protein vti1
Gene namesi
Name:vti1
ORF Names:SPBC3B9.10
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC3B9.10.
PomBaseiSPBC3B9.10. vti1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 191191CytoplasmicSequence analysisAdd
BLAST
Transmembranei192 – 21221Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini213 – 2142VesicularSequence analysis

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • fungal-type vacuole Source: PomBase
  • Golgi apparatus Source: PomBase
  • integral component of Golgi membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Vesicle transport v-SNARE protein vti1PRO_0000218231Add
BLAST

Proteomic databases

MaxQBiP78768.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi277486. 1 interaction.
MINTiMINT-4691179.

Structurei

3D structure databases

ProteinModelPortaliP78768.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the VTI1 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000116573.
InParanoidiP78768.
KOiK08493.
OMAiQMEIEIT.
OrthoDBiEOG7X0VV1.
PhylomeDBiP78768.

Family and domain databases

InterProiIPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
IPR007705. Vesicle_trsprt_v-SNARE_N.
[Graphical view]
PfamiPF05008. V-SNARE. 1 hit.
[Graphical view]
SMARTiSM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.

Sequencei

Sequence statusi: Complete.

P78768-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METYEQEYRL LRADIEEKLN DLSKSGENSV IQSCQRLLNE IDEVIGQMEI
60 70 80 90 100
EITGIPTSER GLVNGRIRSY RSTLEEWRRH LKEEIGKSDR KALFGNRDET
110 120 130 140 150
SGDYIASDQD YDQRTRLLQG TNRLEQSSQR LLESQRIANE TEGIGASILR
160 170 180 190 200
DLHGQRNQLE HSLEMLGDTS GHLDRSLRTL KTMARRLAMN RFFTTAIIAI
210
LVILILLVLY SKFR
Length:214
Mass (Da):24,743
Last modified:January 11, 2001 - v2
Checksum:i641A57E4D7E52A6F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti135 – 1351Q → H in BAA13778 (PubMed:9501991).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89116 mRNA. Translation: BAA13778.1.
CU329671 Genomic DNA. Translation: CAA17790.1.
PIRiT40349.
T42225.
RefSeqiNP_596668.1. NM_001022590.2.

Genome annotation databases

EnsemblFungiiSPBC3B9.10.1; SPBC3B9.10.1:pep; SPBC3B9.10.
GeneIDi2540970.
KEGGispo:SPBC3B9.10.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89116 mRNA. Translation: BAA13778.1.
CU329671 Genomic DNA. Translation: CAA17790.1.
PIRiT40349.
T42225.
RefSeqiNP_596668.1. NM_001022590.2.

3D structure databases

ProteinModelPortaliP78768.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277486. 1 interaction.
MINTiMINT-4691179.

Proteomic databases

MaxQBiP78768.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC3B9.10.1; SPBC3B9.10.1:pep; SPBC3B9.10.
GeneIDi2540970.
KEGGispo:SPBC3B9.10.

Organism-specific databases

EuPathDBiFungiDB:SPBC3B9.10.
PomBaseiSPBC3B9.10. vti1.

Phylogenomic databases

HOGENOMiHOG000116573.
InParanoidiP78768.
KOiK08493.
OMAiQMEIEIT.
OrthoDBiEOG7X0VV1.
PhylomeDBiP78768.

Enzyme and pathway databases

ReactomeiR-SPO-6811440. Retrograde transport at the Trans-Golgi-Network.

Miscellaneous databases

PROiP78768.

Family and domain databases

InterProiIPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
IPR007705. Vesicle_trsprt_v-SNARE_N.
[Graphical view]
PfamiPF05008. V-SNARE. 1 hit.
[Graphical view]
SMARTiSM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
    Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
    DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: PR745.
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiVTI1_SCHPO
AccessioniPrimary (citable) accession number: P78768
Secondary accession number(s): O43039
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 11, 2001
Last modified: June 8, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.