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Protein

Vesicle transport v-SNARE protein vti1

Gene

vti1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-SPO-6811440 Retrograde transport at the Trans-Golgi-Network

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle transport v-SNARE protein vti1
Gene namesi
Name:vti1
ORF Names:SPBC3B9.10
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC3B9.10
PomBaseiSPBC3B9.10 vti1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 191CytoplasmicSequence analysisAdd BLAST191
Transmembranei192 – 212Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini213 – 214VesicularSequence analysis2

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002182311 – 214Vesicle transport v-SNARE protein vti1Add BLAST214

Proteomic databases

MaxQBiP78768
PaxDbiP78768
PRIDEiP78768

PTM databases

iPTMnetiP78768

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi277486, 1 interactor
STRINGi4896.SPBC3B9.10.1

Structurei

3D structure databases

ProteinModelPortaliP78768
SMRiP78768
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the VTI1 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000116573
InParanoidiP78768
KOiK08493
OMAiNYEQQYA
OrthoDBiEOG092C4VGK
PhylomeDBiP78768

Family and domain databases

Gene3Di1.20.58.400, 1 hit
InterProiView protein in InterPro
IPR010989 SNARE
IPR000727 T_SNARE_dom
IPR038407 v-SNARE_N_sf
IPR007705 Vesicle_trsprt_v-SNARE_N
PfamiView protein in Pfam
PF05008 V-SNARE, 1 hit
SMARTiView protein in SMART
SM00397 t_SNARE, 1 hit
SUPFAMiSSF47661 SSF47661, 1 hit

Sequencei

Sequence statusi: Complete.

P78768-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METYEQEYRL LRADIEEKLN DLSKSGENSV IQSCQRLLNE IDEVIGQMEI
60 70 80 90 100
EITGIPTSER GLVNGRIRSY RSTLEEWRRH LKEEIGKSDR KALFGNRDET
110 120 130 140 150
SGDYIASDQD YDQRTRLLQG TNRLEQSSQR LLESQRIANE TEGIGASILR
160 170 180 190 200
DLHGQRNQLE HSLEMLGDTS GHLDRSLRTL KTMARRLAMN RFFTTAIIAI
210
LVILILLVLY SKFR
Length:214
Mass (Da):24,743
Last modified:January 11, 2001 - v2
Checksum:i641A57E4D7E52A6F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti135Q → H in BAA13778 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89116 mRNA Translation: BAA13778.1
CU329671 Genomic DNA Translation: CAA17790.1
PIRiT40349
T42225
RefSeqiNP_596668.1, NM_001022590.2

Genome annotation databases

EnsemblFungiiSPBC3B9.10.1; SPBC3B9.10.1:pep; SPBC3B9.10
GeneIDi2540970
KEGGispo:SPBC3B9.10

Similar proteinsi

Entry informationi

Entry nameiVTI1_SCHPO
AccessioniPrimary (citable) accession number: P78768
Secondary accession number(s): O43039
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 11, 2001
Last modified: March 28, 2018
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health