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P78741 (BBR1_SCHCO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pheromone B beta 1 receptor
Gene names
Name:BBR1
OrganismSchizophyllum commune (Split gill fungus)
Taxonomic identifier5334 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Agaricomycetes › Agaricomycetidae › Agaricales › Schizophyllaceae › Schizophyllum

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Receptor for the BBP1 pheromone, a prenylated mating factor.

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the G-protein coupled receptor 4 family.

Ontologies

Keywords
   Biological processPheromone response
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionG-protein coupled receptor
Receptor
Transducer
Gene Ontology (GO)
   Biological_processresponse to pheromone

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmating-type a-factor pheromone receptor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Pheromone B beta 1 receptor
PRO_0000195073

Regions

Topological domain1 – 33Extracellular Potential
Transmembrane4 – 2421Helical; Potential
Topological domain25 – 339Cytoplasmic Potential
Transmembrane34 – 5421Helical; Potential
Topological domain55 – 6915Extracellular Potential
Transmembrane70 – 9021Helical; Potential
Topological domain91 – 10919Cytoplasmic Potential
Transmembrane110 – 13021Helical; Potential
Topological domain131 – 15020Extracellular Potential
Transmembrane151 – 17121Helical; Potential
Topological domain172 – 20534Cytoplasmic Potential
Transmembrane206 – 22621Helical; Potential
Topological domain227 – 26438Extracellular Potential
Transmembrane265 – 28521Helical; Potential
Topological domain286 – 541256Cytoplasmic Potential
Compositional bias373 – 527155Pro-rich

Sequences

Sequence LengthMass (Da)Tools
P78741 [UniParc].

Last modified July 11, 2001. Version 2.
Checksum: 1EABBE95D548A1AA

FASTA54159,587
        10         20         30         40         50         60 
MHPEFAPVAF LSAASLALPL PWHWRAGNVA TLSIIAWLFI MNMIYGINAV IWAGSARITA 

        70         80         90        100        110        120 
VVYCDITTKL TIGGNFALPA ACLCLCIHLE RVASVRAAQT TAADKRRRTI FELAMCWLLP 

       130        140        150        160        170        180 
IIFMALHYVV QGHRFDIVED FGCRPATYYS IPAIFIVWVP PLTMAAASLV YASLAIRHFM 

       190        200        210        220        230        240 
HRRLSFAMHL QARSSALTTS RYLRLILMAI VQLVWLVVTT AYTLWFSSMT LNLRPWTTWA 

       250        260        270        280        290        300 
DVHSNFGRIQ TWPAIITPAV ILRGACTLWW MVPASTWIFV AFFAFGNDAV EEYKRVLNVV 

       310        320        330        340        350        360 
LSGARRALPE GFLSEKKRDL KGFSLPSFVK GSVPLGDSSS STRKDSLPDK AVLPVNRSVT 

       370        380        390        400        410        420 
MTTTTSTVVS SMPPPYSLPP PPPPQKYTSP LDSLDYSADA DRISISSSVD TSGYTIEILP 

       430        440        450        460        470        480 
ETPSTSSSTP PSPSSPQYPR SPSSQGSHVV DDYYYTSSPQ DSLPHDIPAP PSLPPPTHMP 

       490        500        510        520        530        540 
DEAHISPSHA VPSRPPAFPP YPFARDMRPA ASEPMSPRPI TYPSMSPTHR DIASVFPGGR 


R

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References

[1]"Multiple genes encoding pheromones and a pheromone receptor define the B beta 1 mating-type specificity in Schizophyllum commune."
Vaillancourt L.J., Raudaskoski M., Specht C.A., Raper C.A.
Genetics 146:541-551(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40.
[2]Raper C.A.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U74495 Genomic DNA. Translation: AAB41858.2.

3D structure databases

ModBaseSearch...

Protein family/group databases

GPCRDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR001546. GPCR_Pheromne_A_rcpt.
IPR001499. GPCR_STE3.
[Graphical view]
PfamPF02076. STE3. 1 hit.
[Graphical view]
PRINTSPR00899. GPCRSTE3.
PR00900. PHEROMONEAR.
ProtoNetSearch...

Entry information

Entry nameBBR1_SCHCO
AccessionPrimary (citable) accession number: P78741
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 11, 2001
Last modified: April 3, 2013
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries

SIMILARITY comments

Index of protein domains and families

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