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Protein

Beta-hexosaminidase

Gene

exc2

Organism
Trichoderma harzianum (Hypocrea lixii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei371 – 3711Proton donorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH20. Glycoside Hydrolase Family 20.
mycoCLAPiHEX20B_TRIHA.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
Gene namesi
Name:exc2Imported
OrganismiTrichoderma harzianum (Hypocrea lixii)Imported
Taxonomic identifieri5544 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence analysisAdd
BLAST
Chaini19 – 602584Beta-hexosaminidaseSequence analysisPRO_5004161298Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP78739.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 186168Glycohydro_20b2InterPro annotationAdd
BLAST
Domaini211 – 549339Glyco_hydro_20InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 20 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.30.379.10. 2 hits.
InterProiIPR025705. Beta_hexosaminidase_sua/sub.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR029019. HEX_eukaryotic_N.
[Graphical view]
PfamiPF00728. Glyco_hydro_20. 1 hit.
PF14845. Glycohydro_20b2. 1 hit.
[Graphical view]
PIRSFiPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
PRINTSiPR00738. GLHYDRLASE20.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 2 hits.

Sequencei

Sequence statusi: Complete.

P78739-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSRAIVAAL ALSGPAFALW PVPKHSSTGN DTLFIDQTVQ VTYNGEQVWW
60 70 80 90 100
TPPYDDPGSP DFAETRIDDQ QVTYTAGYVP PSGPHFTSKE IVQGGVSRTF
110 120 130 140 150
GAIFQQGFVP WMLRERDSNS EPNLGGTRIR TLQIIQTQHD SANTFKPLNG
160 170 180 190 200
AVNESYALDV DAKGHASLTA PSSTGILRGL ETFSQLFFKH SSGTAWYTQL
210 220 230 240 250
APVSIRDEPK YPHRGLLLDV SRHWFEVSDI ERTIDALAMN KMNVLHLHAT
260 270 280 290 300
DTQSWPLEIP SLPLLAEKGA YHKGLSYSPS DLASIQEYGV HRGVQVIVEI
310 320 330 340 350
DMPGHVGIDK AYPGLSNAYG VNPWQWYCAQ PPCGSFKLNN TDVEKFIDKL
360 370 380 390 400
FEDLLPRLSP YSAYFHTGGD EYKANNSLLD PALRTNDMNT LQPMLQRFLD
410 420 430 440 450
HVHGKVRDLG LVPMVWEEMI LDWNATLGKD VVAQTWLGGG AIQKLAQAGY
460 470 480 490 500
KVIDSSNDFY YLDCGRGEWL DFANGDPFNN NYPFLDWCDP TKNWKLMYSH
510 520 530 540 550
EPTDGVSDDL KKNVIGGEVA VWTETIDPTS LDSIIWPRAG AAAEIWWSGK
560 570 580 590 600
IDEKGQNRSQ IDARPRLSEQ RERMLARGVR GTPITQLWCS QVDVHNCESG

NY
Length:602
Mass (Da):67,304
Last modified:May 1, 1997 - v1
Checksum:i67535E4A0E9347D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80070 mRNA. Translation: AAB47061.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80070 mRNA. Translation: AAB47061.1.

3D structure databases

ProteinModelPortaliP78739.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH20. Glycoside Hydrolase Family 20.
mycoCLAPiHEX20B_TRIHA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.30.379.10. 2 hits.
InterProiIPR025705. Beta_hexosaminidase_sua/sub.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR029019. HEX_eukaryotic_N.
[Graphical view]
PfamiPF00728. Glyco_hydro_20. 1 hit.
PF14845. Glycohydro_20b2. 1 hit.
[Graphical view]
PIRSFiPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
PRINTSiPR00738. GLHYDRLASE20.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning and expression in S. cerevisiae of two exochitinases from Trichoderma harzianum."
    Draborg H., Kauppinen S., Dalboge H., Christgau S.
    Biochem. Mol. Biol. Int. 36:781-791(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP78739_TRIHA
AccessioniPrimary (citable) accession number: P78739
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: December 9, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.