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Protein

Beta-hexosaminidase

Gene

exc1

Organism
Trichoderma harzianum (Hypocrea lixii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei349 – 3491Proton donorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH20. Glycoside Hydrolase Family 20.
mycoCLAPiHEX20A_TRIHA.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
Gene namesi
Name:exc1Imported
OrganismiTrichoderma harzianum (Hypocrea lixii)Imported
Taxonomic identifieri5544 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 578559Beta-hexosaminidaseSequence analysisPRO_5004161601Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP78738.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 163144Glycohydro_20b2InterPro annotationAdd
BLAST
Domaini188 – 527340Glyco_hydro_20InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 20 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.30.379.10. 1 hit.
InterProiIPR025705. Beta_hexosaminidase_sua/sub.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR029019. HEX_eukaryotic_N.
[Graphical view]
PfamiPF00728. Glyco_hydro_20. 1 hit.
PF14845. Glycohydro_20b2. 1 hit.
[Graphical view]
PIRSFiPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
PRINTSiPR00738. GLHYDRLASE20.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 1 hit.

Sequencei

Sequence statusi: Complete.

P78738-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPKAIIAIA ALAFSPANAL WPIPQKISTG DSVLFIDQAV RVTYNGVPII
60 70 80 90 100
PIGYNPPASS NFDSRQIVQA AVSRAFQNIF STNYVPWKLH PRNSNFEPKV
110 120 130 140 150
APQNRIQSIS IQQTGKDTSK TFKPRAGDVD ESYSLTISKN GQVNISAKSS
160 170 180 190 200
TGVLHALETF SQLFYKHSAG PFYYTTQAPV SITDAPKYPH RGIMLDLARN
210 220 230 240 250
YQTIDDIKRT IDAMSWNKLN RLHLHITDSQ SWPLVIPSLP KLSQAGAYHP
260 270 280 290 300
SLVYTPADLA GIFQYGVARG VEVITEIDMP GHIGVIELAY SDLIVAYEEM
310 320 330 340 350
PYQYYCAEPP CGAFSINNTK VYSFLDTLFD DLLPRVAPYS AYFHTGGDEL
360 370 380 390 400
NANDSMLDSH IKSNETSVLQ PLLQKFINFA HSKVRAAGLS PFVWEEMVTT
410 420 430 440 450
WNLTLGSDTV VQSWLGGDAV KNLAESGHKV IDTDYNFYYL DCGRGQWVNF
460 470 480 490 500
PPGDSYNTYY PFNDWCQPTK NWRLIYSHDP AANVSASAAK NVLGGELAIW
510 520 530 540 550
SEMIDASNLD NIIWPRGSAA GEVWWSGNTD ASGEQRSQLD VVPRLNEFRE
560 570
RLLARGVSAF PIQMTYCTQL NATACTLF
Length:578
Mass (Da):64,234
Last modified:May 1, 1997 - v1
Checksum:iF5344BE0AAAC23D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80069 mRNA. Translation: AAB47060.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80069 mRNA. Translation: AAB47060.1.

3D structure databases

ProteinModelPortaliP78738.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH20. Glycoside Hydrolase Family 20.
mycoCLAPiHEX20A_TRIHA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.30.379.10. 1 hit.
InterProiIPR025705. Beta_hexosaminidase_sua/sub.
IPR029018. Chitobiase/Hex_dom_2-like.
IPR015883. Glyco_hydro_20_cat.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR029019. HEX_eukaryotic_N.
[Graphical view]
PfamiPF00728. Glyco_hydro_20. 1 hit.
PF14845. Glycohydro_20b2. 1 hit.
[Graphical view]
PIRSFiPIRSF001093. B-hxosamndse_ab_euk_. 1 hit.
PRINTSiPR00738. GLHYDRLASE20.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF55545. SSF55545. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiP78738_TRIHA
AccessioniPrimary (citable) accession number: P78738
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: December 9, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.