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Protein
Submitted name:

Pyruvate dehydrogenase E1-alpha-subunit

Gene

PDHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E1-alpha-subunitImported
Gene namesi
Name:PDHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369134.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 59E1_dhInterPro annotationAdd BLAST59

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR001017. DH_E1.
IPR029061. THDP-binding.
PfamiView protein in Pfam
PF00676. E1_dh. 1 hit.
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Fragment.

P78557-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
YRTREEIQEV RSKSDPIMLL KDRMVNSNLA SVEELKEIDV EVXKEIEDAA

QFATADPEP
Length:59
Mass (Da):6,789
Last modified:May 1, 1997 - v1
Checksum:i3B594521A61278A5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei59Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75937 Genomic DNA. Translation: AAB39727.1.
U75938 Genomic DNA. Translation: AAB39728.1.
UniGeneiHs.530331.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75937 Genomic DNA. Translation: AAB39727.1.
U75938 Genomic DNA. Translation: AAB39728.1.
UniGeneiHs.530331.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369134.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.

Miscellaneous databases

ChiTaRSiPDHA1. human.

Family and domain databases

InterProiView protein in InterPro
IPR001017. DH_E1.
IPR029061. THDP-binding.
PfamiView protein in Pfam
PF00676. E1_dh. 1 hit.
SUPFAMiSSF52518. SSF52518. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiP78557_HUMAN
AccessioniPrimary (citable) accession number: P78557
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 10, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.