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Protein
Submitted name:

Pyruvate dehydrogenase E1-alpha-subunit

Gene

PDHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

PyruvateImported

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E1-alpha-subunitImported
Gene namesi
Name:PDHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiP78557.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369134.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5959E1_dhInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Fragment.

P78557-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
YRTREEIQEV RSKSDPIMLL KDRMVNSNLA SVEELKEIDV EVXKEIEDAA

QFATADPEP
Length:59
Mass (Da):6,789
Last modified:May 1, 1997 - v1
Checksum:i3B594521A61278A5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei59 – 591Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75937 Genomic DNA. Translation: AAB39727.1.
U75938 Genomic DNA. Translation: AAB39728.1.
UniGeneiHs.530331.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75937 Genomic DNA. Translation: AAB39727.1.
U75938 Genomic DNA. Translation: AAB39728.1.
UniGeneiHs.530331.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369134.

Proteomic databases

PeptideAtlasiP78557.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.

Miscellaneous databases

ChiTaRSiPDHA1. human.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiP78557_HUMAN
AccessioniPrimary (citable) accession number: P78557
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.