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P78552

- I13R1_HUMAN

UniProt

P78552 - I13R1_HUMAN

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Protein
Interleukin-13 receptor subunit alpha-1
Gene
IL13RA1, IL13R, IL13RA
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

GO - Molecular functioni

  1. interleukin-13 receptor activity Source: Ensembl
  2. protein binding Source: IntAct

GO - Biological processi

  1. cell surface receptor signaling pathway Source: ProtInc
  2. positive regulation of B cell proliferation Source: Ensembl
  3. positive regulation of immunoglobulin production Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Enzyme and pathway databases

SignaLinkiP78552.

Names & Taxonomyi

Protein namesi
Recommended name:
Interleukin-13 receptor subunit alpha-1
Short name:
IL-13 receptor subunit alpha-1
Short name:
IL-13R subunit alpha-1
Short name:
IL-13R-alpha-1
Short name:
IL-13RA1
Alternative name(s):
Cancer/testis antigen 19
Short name:
CT19
CD_antigen: CD213a1
Gene namesi
Name:IL13RA1
Synonyms:IL13R, IL13RA
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:5974. IL13RA1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 343322Extracellular Reviewed prediction
Add
BLAST
Transmembranei344 – 36724Helical; Reviewed prediction
Add
BLAST
Topological domaini368 – 42760Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. interleukin-13 receptor complex Source: ProtInc
  2. plasma membrane Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA200.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed prediction
Add
BLAST
Chaini22 – 427406Interleukin-13 receptor subunit alpha-1
PRO_0000010939Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi37 – 371N-linked (GlcNAc...) Reviewed prediction
Glycosylationi61 – 611N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi62 ↔ 1021 Publication
Disulfide bondi95 ↔ 1171 Publication
Glycosylationi105 – 1051N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi134 ↔ 1441 Publication
Glycosylationi138 – 1381N-linked (GlcNAc...) Reviewed prediction
Glycosylationi157 – 1571N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi173 ↔ 1851 Publication
Glycosylationi235 – 2351N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi257 ↔ 3201 Publication
Glycosylationi265 – 2651N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi282 ↔ 2961 Publication
Glycosylationi293 – 2931N-linked (GlcNAc...) Reviewed prediction
Glycosylationi329 – 3291N-linked (GlcNAc...) Reviewed prediction
Glycosylationi341 – 3411N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP78552.
PaxDbiP78552.
PRIDEiP78552.

PTM databases

PhosphoSiteiP78552.

Expressioni

Tissue specificityi

Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

Gene expression databases

ArrayExpressiP78552.
BgeeiP78552.
CleanExiHS_IL13RA1.
GenevestigatoriP78552.

Organism-specific databases

HPAiHPA001008.
HPA001587.

Interactioni

Subunit structurei

Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
IL13P352254EBI-1391535,EBI-1647828
IL4P051123EBI-1391535,EBI-367025
TRAF3IP1Q8TDR03EBI-1391535,EBI-928811

Protein-protein interaction databases

BioGridi109811. 5 interactions.
DIPiDIP-3225N.
IntActiP78552. 6 interactions.
STRINGi9606.ENSP00000360730.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi36 – 438
Turni44 – 463
Beta strandi47 – 537
Beta strandi66 – 683
Helixi71 – 733
Beta strandi77 – 8711
Beta strandi94 – 1007
Beta strandi114 – 1185
Turni125 – 1273
Beta strandi130 – 1378
Turni138 – 1403
Beta strandi141 – 1477
Beta strandi158 – 1669
Beta strandi176 – 1794
Beta strandi182 – 1887
Beta strandi202 – 2087
Beta strandi216 – 2205
Beta strandi222 – 2276
Beta strandi232 – 2398
Beta strandi242 – 2487
Helixi252 – 2554
Beta strandi258 – 2658
Beta strandi267 – 2693
Beta strandi273 – 2786
Beta strandi285 – 2884
Beta strandi292 – 2998
Beta strandi309 – 3168
Helixi318 – 3203
Beta strandi334 – 3374

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BPNX-ray3.02C29-342[»]
3BPOX-ray3.00C29-342[»]
4HWBX-ray2.61A223-336[»]
ProteinModelPortaliP78552.
SMRiP78552. Positions 30-338.

Miscellaneous databases

EvolutionaryTraceiP78552.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 12390Fibronectin type-III 1
Add
BLAST
Domaini128 – 22699Fibronectin type-III 2
Add
BLAST
Domaini227 – 339113Fibronectin type-III 3
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi327 – 3315WSXWS motif
Motifi374 – 3829Box 1 motif

Domaini

The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG44457.
HOGENOMiHOG000230941.
HOVERGENiHBG052060.
InParanoidiP78552.
KOiK05076.
OMAiNKLCYED.
OrthoDBiEOG71P2B1.
PhylomeDBiP78552.
TreeFamiTF331549.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR015321. IL-6_rcpt_alpha-bd.
IPR003532. Short_hematopoietin_rcpt_2_CS.
[Graphical view]
PfamiPF09240. IL6Ra-bind. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
PROSITEiPS50853. FN3. 3 hits.
PS01356. HEMATOPO_REC_S_F2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P78552-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MEWPARLCGL WALLLCAGGG GGGGGAAPTE TQPPVTNLSV SVENLCTVIW    50
TWNPPEGASS NCSLWYFSHF GDKQDKKIAP ETRRSIEVPL NERICLQVGS 100
QCSTNESEKP SILVEKCISP PEGDPESAVT ELQCIWHNLS YMKCSWLPGR 150
NTSPDTNYTL YYWHRSLEKI HQCENIFREG QYFGCSFDLT KVKDSSFEQH 200
SVQIMVKDNA GKIKPSFNIV PLTSRVKPDP PHIKNLSFHN DDLYVQWENP 250
QNFISRCLFY EVEVNNSQTE THNVFYVQEA KCENPEFERN VENTSCFMVP 300
GVLPDTLNTV RIRVKTNKLC YEDDKLWSNW SQEMSIGKKR NSTLYITMLL 350
IVPVIVAGAI IVLLLYLKRL KIIIFPPIPD PGKIFKEMFG DQNDDTLHWK 400
KYDIYEKQTK EETDSVVLIE NLKKASQ 427
Length:427
Mass (Da):48,760
Last modified:May 1, 1997 - v1
Checksum:i5983B3E8F554107B
GO
Isoform 2 (identifier: P78552-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     278-279: QE → RF
     280-427: Missing.

Show »
Length:279
Mass (Da):31,659
Checksum:iE74141FE9F8E9EBB
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei278 – 2792QE → RF in isoform 2.
VSP_055587
Alternative sequencei280 – 427148Missing in isoform 2.
VSP_055588Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti130 – 1301T → I in AAB37127. 1 Publication
Sequence conflicti358 – 3581G → D in AAB37127. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y10659 mRNA. Translation: CAA71669.1.
Y09328 mRNA. Translation: CAA70508.1.
U62858 mRNA. Translation: AAB37127.1.
U81379 mRNA. Translation: AAD00510.3.
U81380 mRNA. Translation: AAD00511.2.
AK313467 mRNA. Translation: BAG36253.1.
AL391280 Genomic DNA. Translation: CAI41410.1.
CH471161 Genomic DNA. Translation: EAW89893.1.
BC009960 mRNA. Translation: AAH09960.1.
CCDSiCCDS14573.1.
RefSeqiNP_001551.1. NM_001560.2.
UniGeneiHs.496646.

Genome annotation databases

EnsembliENST00000371642; ENSP00000360705; ENSG00000131724.
ENST00000371666; ENSP00000360730; ENSG00000131724.
GeneIDi3597.
KEGGihsa:3597.
UCSCiuc004eqs.3. human.

Polymorphism databases

DMDMi2494718.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y10659 mRNA. Translation: CAA71669.1 .
Y09328 mRNA. Translation: CAA70508.1 .
U62858 mRNA. Translation: AAB37127.1 .
U81379 mRNA. Translation: AAD00510.3 .
U81380 mRNA. Translation: AAD00511.2 .
AK313467 mRNA. Translation: BAG36253.1 .
AL391280 Genomic DNA. Translation: CAI41410.1 .
CH471161 Genomic DNA. Translation: EAW89893.1 .
BC009960 mRNA. Translation: AAH09960.1 .
CCDSi CCDS14573.1.
RefSeqi NP_001551.1. NM_001560.2.
UniGenei Hs.496646.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3BPN X-ray 3.02 C 29-342 [» ]
3BPO X-ray 3.00 C 29-342 [» ]
4HWB X-ray 2.61 A 223-336 [» ]
ProteinModelPortali P78552.
SMRi P78552. Positions 30-338.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 109811. 5 interactions.
DIPi DIP-3225N.
IntActi P78552. 6 interactions.
STRINGi 9606.ENSP00000360730.

PTM databases

PhosphoSitei P78552.

Polymorphism databases

DMDMi 2494718.

Proteomic databases

MaxQBi P78552.
PaxDbi P78552.
PRIDEi P78552.

Protocols and materials databases

DNASUi 3597.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000371642 ; ENSP00000360705 ; ENSG00000131724 .
ENST00000371666 ; ENSP00000360730 ; ENSG00000131724 .
GeneIDi 3597.
KEGGi hsa:3597.
UCSCi uc004eqs.3. human.

Organism-specific databases

CTDi 3597.
GeneCardsi GC0XP117861.
HGNCi HGNC:5974. IL13RA1.
HPAi HPA001008.
HPA001587.
MIMi 300119. gene.
neXtProti NX_P78552.
PharmGKBi PA200.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG44457.
HOGENOMi HOG000230941.
HOVERGENi HBG052060.
InParanoidi P78552.
KOi K05076.
OMAi NKLCYED.
OrthoDBi EOG71P2B1.
PhylomeDBi P78552.
TreeFami TF331549.

Enzyme and pathway databases

SignaLinki P78552.

Miscellaneous databases

ChiTaRSi IL13RA1. human.
EvolutionaryTracei P78552.
GeneWikii Interleukin_13_receptor,_alpha_1.
GenomeRNAii 3597.
NextBioi 14057.
PROi P78552.
SOURCEi Search...

Gene expression databases

ArrayExpressi P78552.
Bgeei P78552.
CleanExi HS_IL13RA1.
Genevestigatori P78552.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR015321. IL-6_rcpt_alpha-bd.
IPR003532. Short_hematopoietin_rcpt_2_CS.
[Graphical view ]
Pfami PF09240. IL6Ra-bind. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 2 hits.
PROSITEi PS50853. FN3. 3 hits.
PS01356. HEMATOPO_REC_S_F2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex."
    Miloux B., Laurent P., Bonnin O., Lupker J., Caput D., Vita N., Ferrara P.
    FEBS Lett. 401:163-166(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Carcinoma.
  2. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: B-cell.
  3. "cDNA cloning and characterization of the human interleukin 13 receptor alpha chain."
    Aman M.J., Tayebi N., Obiri N.I., Puri R.K., Modi W.S., Leonard W.J.
    J. Biol. Chem. 271:29265-29270(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: T-cell.
  4. Wada M., Hisano T., Kuwano M.
    Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Hippocampus.
  6. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Pancreas.
  9. "MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network."
    Ling L., Goeddel D.V.
    J. Biol. Chem. 275:23852-23860(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH TRAF3IP1.
  10. "Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system."
    LaPorte S.L., Juo Z.S., Vaclavikova J., Colf L.A., Qi X., Heller N.M., Keegan A.D., Garcia K.C.
    Cell 132:259-272(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 29-342 IN COMPLEXES WITH IL4; IL4RA AND IL13, DISULFIDE BONDS, SUBUNIT.

Entry informationi

Entry nameiI13R1_HUMAN
AccessioniPrimary (citable) accession number: P78552
Secondary accession number(s): O95646
, Q5JSL4, Q99656, Q9UDY5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 1, 1997
Last modified: September 3, 2014
This is version 139 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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