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P78517

- P78517_HUMAN

UniProt

P78517 - P78517_HUMAN

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Protein
Submitted name:

68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. fibroblast migration Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alphaImported (EC:2.7.1.68Imported)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
  2. ruffle membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiP78517.
ExpressionAtlasiP78517. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliP78517.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains PIPK domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000193876.

Family and domain databases

Gene3Di3.30.810.10. 1 hit.
InterProiIPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
[Graphical view]
PANTHERiPTHR23086. PTHR23086. 1 hit.
PfamiPF01504. PIP5K. 1 hit.
[Graphical view]
PROSITEiPS51455. PIPK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P78517 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
QKALYSTAME SIQGEARRGG TMETDDHMGG IPARNSKGER LLLYIGIIDI
60 70 80 90 100
LQSYRFVKKL EHSWKALVHD GDTVSVHRPG FYAERFQRFM CNTVFKKIPL
110 120 130 140 150
KPSPSKKFRS GSSFSRRAGS SGNSCITYQP SVSGEHKAQV TTKAEVEPGV
160 170 180 190 200
HLGRPDVLPQ TPPLEEISEG SPIPDPSFSP LVGETLQMLT TSTTLEKLEV

AESEFTH
Length:207
Mass (Da):22,864
Last modified:May 1, 1997 - v1
Checksum:i9A9B0027A6B08047
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U78578 mRNA. Translation: AAC50913.1.
UniGeneiHs.655131.
Hs.661888.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U78578 mRNA. Translation: AAC50913.1 .
UniGenei Hs.655131.
Hs.661888.

3D structure databases

ProteinModelPortali P78517.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi P78517.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000193876.

Gene expression databases

Bgeei P78517.
ExpressionAtlasi P78517. baseline and differential.

Family and domain databases

Gene3Di 3.30.810.10. 1 hit.
InterProi IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
[Graphical view ]
PANTHERi PTHR23086. PTHR23086. 1 hit.
Pfami PF01504. PIP5K. 1 hit.
[Graphical view ]
PROSITEi PS51455. PIPK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family."
    Loijens J.C., Anderson R.A.
    J. Biol. Chem. 271:32937-32943(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP78517_HUMAN
AccessioniPrimary (citable) accession number: P78517
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.