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P78517

- P78517_HUMAN

UniProt

P78517 - P78517_HUMAN

Protein
Submitted name:

68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 May 1997)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fibroblast migration Source: Ensembl

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alphaImported (EC:2.7.1.68Imported)
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: Ensembl
    2. ruffle membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiP78517.
    BgeeiP78517.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliP78517.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains PIPK domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000193876.

    Family and domain databases

    Gene3Di3.30.810.10. 1 hit.
    InterProiIPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    [Graphical view]
    PANTHERiPTHR23086. PTHR23086. 1 hit.
    PfamiPF01504. PIP5K. 1 hit.
    [Graphical view]
    PROSITEiPS51455. PIPK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P78517-1 [UniParc]FASTAAdd to Basket

    « Hide

    QKALYSTAME SIQGEARRGG TMETDDHMGG IPARNSKGER LLLYIGIIDI    50
    LQSYRFVKKL EHSWKALVHD GDTVSVHRPG FYAERFQRFM CNTVFKKIPL 100
    KPSPSKKFRS GSSFSRRAGS SGNSCITYQP SVSGEHKAQV TTKAEVEPGV 150
    HLGRPDVLPQ TPPLEEISEG SPIPDPSFSP LVGETLQMLT TSTTLEKLEV 200
    AESEFTH 207
    Length:207
    Mass (Da):22,864
    Last modified:May 1, 1997 - v1
    Checksum:i9A9B0027A6B08047
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U78578 mRNA. Translation: AAC50913.1.
    UniGeneiHs.655131.
    Hs.661888.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U78578 mRNA. Translation: AAC50913.1 .
    UniGenei Hs.655131.
    Hs.661888.

    3D structure databases

    ProteinModelPortali P78517.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi P78517.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000193876.

    Gene expression databases

    ArrayExpressi P78517.
    Bgeei P78517.

    Family and domain databases

    Gene3Di 3.30.810.10. 1 hit.
    InterProi IPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    [Graphical view ]
    PANTHERi PTHR23086. PTHR23086. 1 hit.
    Pfami PF01504. PIP5K. 1 hit.
    [Graphical view ]
    PROSITEi PS51455. PIPK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family."
      Loijens J.C., Anderson R.A.
      J. Biol. Chem. 271:32937-32943(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiP78517_HUMAN
    AccessioniPrimary (citable) accession number: P78517
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 1997
    Last sequence update: May 1, 1997
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.