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Protein
Submitted name:

RB1 protein

Gene

RB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RB1 proteinImported
Gene namesi
Name:RB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiP78495.
PRIDEiP78495.

Expressioni

Gene expression databases

BgeeiP78495.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000267163.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5454Rb_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1010. Eukaryota.
ENOG410XQF7. LUCA.

Family and domain databases

InterProiIPR033057. RB1.
IPR015030. RB_C.
IPR028309. RB_fam.
[Graphical view]
PANTHERiPTHR13742. PTHR13742. 1 hit.
PTHR13742:SF21. PTHR13742:SF21. 1 hit.
PfamiPF08934. Rb_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P78495-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PPTLSPIPHI PRSPYKFPSS PLRIPGGNIY ISPLKSPYKI SEGLPTPTKM

TPRS
Length:54
Mass (Da):5,911
Last modified:May 1, 1997 - v1
Checksum:iF9791050A231293E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei54 – 541Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L41910 Genomic DNA. Translation: AAA65746.1.
UniGeneiHs.408528.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L41910 Genomic DNA. Translation: AAA65746.1.
UniGeneiHs.408528.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000267163.

Proteomic databases

PaxDbiP78495.
PRIDEiP78495.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1010. Eukaryota.
ENOG410XQF7. LUCA.

Miscellaneous databases

ChiTaRSiRB1. human.

Gene expression databases

BgeeiP78495.

Family and domain databases

InterProiIPR033057. RB1.
IPR015030. RB_C.
IPR028309. RB_fam.
[Graphical view]
PANTHERiPTHR13742. PTHR13742. 1 hit.
PTHR13742:SF21. PTHR13742:SF21. 1 hit.
PfamiPF08934. Rb_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Detection of heterozygous mutations in the RB1 gene in retinoblastoma patients using single-strand conformation polymorphism analysis and polymerase chain reaction sequencing."
    Hogg A., Onadim Z., Baird P.N., Cowell J.K.
    Oncogene 7:1445-1451(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP78495_HUMAN
AccessioniPrimary (citable) accession number: P78495
Secondary accession number(s): P78496, P78497
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: June 8, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.