Unreviewed, UniProtKB/TrEMBL P78470 (P78470_HUMAN)

Names and origin

Protein names	Submitted name:     Growth hormone-releasing hormone receptor form a EMBL AAB18632.1
Organism	Homo sapiens (Human) EMBL AAB18632.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	76 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Cellular component	Cell membrane Spearmint SPM000832 Membrane
Domain	Transmembrane Spearmint SPM000832
Molecular function	G-protein coupled receptor Spearmint SPM000832 Receptor Transducer
Gene Ontology (GO)
Biological process	activation of adenylate cyclase activity Inferred from electronic annotation. Source: Compara activation of adenylate cyclase activity by G-protein signaling pathway Inferred from electronic annotation. Source: Compara cell maturation Inferred from electronic annotation. Source: Compara cellular response to insulin stimulus Inferred from electronic annotation. Source: Compara determination of adult life span Inferred from electronic annotation. Source: Compara hormone metabolic process Inferred from electronic annotation. Source: Compara lactation Inferred from electronic annotation. Source: Compara mammary gland development Inferred from electronic annotation. Source: Compara positive regulation of cAMP metabolic process Inferred from electronic annotation. Source: Compara positive regulation of cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of growth hormone secretion Inferred from electronic annotation. Source: Compara positive regulation of multicellular organism growth Inferred from mutant phenotype. Source: MGI regulation of insulin-like growth factor receptor signaling pathway Inferred from electronic annotation. Source: Compara regulation of protein metabolic process Inferred from electronic annotation. Source: Compara regulation of steroid hormone receptor signaling pathway Inferred from electronic annotation. Source: Compara somatotropin secreting cell development Inferred from electronic annotation. Source: Compara water homeostasis Inferred from electronic annotation. Source: Compara
Cellular component	cell surface Inferred from electronic annotation. Source: Compara integral to membrane Inferred from direct assay. Source: MGI plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	growth hormone-releasing hormone receptor activity Inferred from electronic annotation. Source: Compara peptide hormone binding Inferred from electronic annotation. Source: Compara protein binding Inferred from physical interaction. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAB18632.1
	Non-terminal residue	76	1	EMBL AAB18632.1

Sequences

	Sequence		Length	Mass (Da)
	P78470-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: F8E10BABB41C0D97	FASTA	76	8,796
	10 20 30 40 50 60 CKLAFEDIAC WDLDDTSPYW WIIKGPIVLS VGVNFGLFLN IIRILVRKLE PAQGSLHTQS 70 QYWRLSKSTL FLIPLF

References

[1]	"Identification of human growth hormone-releasing hormone receptor splicing variants." Tang J., Lagace G., Castagne J., Collu R. J. Clin. Endocrinol. Metab. 80:2381-2387(1995) [PubMed: 7629234] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U17579 Genomic DNA. Translation: AAB18632.1.
IPI	IPI00477889.
UniGene	Hs.767
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000106128. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:4266. GHRHR.
Phylogenomic databases
HOVERGEN	P78470.
Gene expression databases
ArrayExpress	P78470.
Bgee	P78470.
Family and domain databases
InterPro	IPR017981. GPCR_2-like. IPR003288. GPCR_2_GHRH_rcpt. IPR000832. GPCR_2_secretin-like. [Graphical view]
PANTHER	PTHR12011:SF26. GHR_rcpt. 1 hit.
Pfam	PF00002. 7tm_2. 1 hit. [Graphical view]
PRINTS	PR00249. GPCRSECRETIN.
PROSITE	PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P78470_HUMAN

Accession

Primary (citable) accession number: P78470

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	April 14, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)