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Protein
Submitted name:

Tyrosine kinase

Gene

c-fgr

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

SignaLinkiP78453

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine kinaseImported
Gene namesi
Name:c-fgrImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28135

PTM / Processingi

Proteomic databases

PeptideAtlasiP78453

Expressioni

Gene expression databases

GenevisibleiP78453 HS

Structurei

3D structure databases

ProteinModelPortaliP78453
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 138SH3InterPro annotationAdd BLAST62
Domaini144 – 177SH2InterPro annotationAdd BLAST34

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0197 Eukaryota
COG0515 LUCA
HOVERGENiHBG008761
KOiK08891

Family and domain databases

Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF00018 SH3_1, 1 hit
PRINTSiPR00401 SH2DOMAIN
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Fragment.

P78453-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCVFCKKLE PVATAKEDAG LEGDFRSYGA ADHYGPDPTK ARPASSFAHI
60 70 80 90 100
PNYSNFSSQA INPGFLDSGT IRGVSGIGVT LFIALYDYEA RTEDDLTFTK
110 120 130 140 150
GEKFHILNNT EGDWWEARSL SSGKTGCIPS NYVAPVDSIQ AEEWYFGKIG
160 170
RKDAERQLLS PGNPQGAFLI RESETTK
Length:177
Mass (Da):19,354
Last modified:May 1, 1997 - v1
Checksum:i11ACD7F3BAF3D43E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei177Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M27454 mRNA Translation: AAA35679.1
RefSeqiNP_001036194.1, NM_001042729.1
UniGeneiHs.1422

Genome annotation databases

GeneIDi2268
KEGGihsa:2268

Similar proteinsi

Entry informationi

Entry nameiP78453_HUMAN
AccessioniPrimary (citable) accession number: P78453
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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