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Protein
Submitted name:

Butyrophilin

Gene

BT3.3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
ButyrophilinImported
Gene namesi
Name:BT3.3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 731704Sequence analysisPRO_5004161346Add
BLAST

Proteomic databases

PeptideAtlasiP78409.
PRIDEiP78409.

Structurei

3D structure databases

ProteinModelPortaliP78409.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 140117Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini162 – 23473Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini480 – 674195B30.2/SPRYInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains B30.2/SPRY domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG050747.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR001870. B30.2/SPRY.
IPR003879. Butyrophylin.
IPR013320. ConA-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR006574. PRY.
IPR003877. SPRY_dom.
[Graphical view]
PfamiPF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSiPR01407. BUTYPHLNCDUF.
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
SM00589. PRY. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50188. B302_SPRY. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P78409-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSLAFLLL NFHVSLFLVQ LLTPCSAQFS VLGPSGPILA MVGEDADLPC
60 70 80 90 100
HLFPTMSAET MELRWVSSSL RQVVNVYADG KEVEYRQSAP YRGRTSILRD
110 120 130 140 150
GITAGKAALR IHNVTASDSG KYLCYFQHGD FYEKAPVELK VAALGSDLHI
160 170 180 190 200
EVKGYDDGGI HLECRSTGWY PQPQINWSDS KGENIPAVEG PVNVYGVGLY
210 220 230 240 250
AVPPPVIMTG TSGGGVSCII TNSLLGLEKT ASISIADPFI QGGAPARXXX
260 270 280 290 300
GPGXGTLAYF XVAXSWQGAS YFLWRQQKEX IGLSRETERE REMKEMGYXA
310 320 330 340 350
TEQEISAKRS LQEELKWRKI QYMARGEESS SDTKKSALML KWKKALFKPG
360 370 380 390 400
DKMLQMRVSP CKINWMYSKI YCRKGELIKF ISGRVKIENK PLSIKHQWAX
410 420 430 440 450
SMWGGKQQKC XKRILVASWG RIRVLGKAXT DLTFISPLVT RPLGLSPMTL
460 470 480 490 500
MRESHSGQAR DTGFWKDLLS MAQALHAVAL KSRKNGRPHG HLLKLSAADV
510 520 530 540 550
ILYPDMANAI LLVSEDQRSV QRAEEPHDLP DNPERFEWRY CVLGCESFMS
560 570 580 590 600
ERHYWEVEVG DRKEWHIGVC SKNVERKKVW VKMTPENGYW TMGLTDGNKY
610 620 630 640 650
RALTEPRTNL KLPEPPRKVG VILDYETGHI SFYNATDGSH IYTFLHASSS
660 670 680 690 700
EPLYPVFRIL TLEPTALTVC PIPKVESSPD PDLVPDHSLE IPLTPGLANE
710 720 730
SGEPQAEVTS LLLPAQPGAK GLTLHNSQSE P
Length:731
Mass (Da):81,407
Last modified:November 1, 1998 - v2
Checksum:i2F0E0A32B73685F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U97502, U97500, U97501 Genomic DNA. Translation: AAC02656.1.
UniGeneiHs.376046.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U97502, U97500, U97501 Genomic DNA. Translation: AAC02656.1.
UniGeneiHs.376046.

3D structure databases

ProteinModelPortaliP78409.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiP78409.
PRIDEiP78409.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG050747.

Miscellaneous databases

ChiTaRSiBTN3A2. human.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR001870. B30.2/SPRY.
IPR003879. Butyrophylin.
IPR013320. ConA-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR006574. PRY.
IPR003877. SPRY_dom.
[Graphical view]
PfamiPF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSiPR01407. BUTYPHLNCDUF.
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
SM00589. PRY. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50188. B302_SPRY. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex."
    Tazi-Ahnini R., Henry J., Offer C., Bouissou-Bouchouata C., Mather I.H., Pontarotti P.
    Immunogenetics 47:55-63(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Tazi Ahnini R., Henry J., Offer C., Bouchouata C., Mather I.H., Pontarotti P.
    Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiP78409_HUMAN
AccessioniPrimary (citable) accession number: P78409
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.