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P78033 (G6PI_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:MPN_250
ORF Names:MP582
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180686

Sites

Active site2841Proton donor By similarity
Active site3051 By similarity
Active site4201 By similarity

Sequences

Sequence LengthMass (Da)Tools
P78033 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: BBF48166F3DCBA70

FASTA43048,834
        10         20         30         40         50         60 
MESKWLTVDT KHLYGFDEAI FIQKYQKKVN QIHQQFLNQQ LPDGHMNGWY SQPDQDHKGL 

        70         80         90        100        110        120 
LKQINTIAKQ FNALKVTDIV YLGIGGSYTG IRAILDFLKP EQKANIKVHF VPDISAFNIA 

       130        140        150        160        170        180 
AVARAIKGKS WALVVTSKSG RTLEPAVTFR YFRNLLHKQY KQKHALRTVV ITDAVKGLLV 

       190        200        210        220        230        240 
GMSNQYGYAH LTIPSNIGGR FSTLSPAGLL LAKLCGHDPK QLLLGTLTAK QELANSDLNT 

       250        260        270        280        290        300 
NSAYYYAALR HWLYTTKKLK IEVTVAYHSA YEYLLLQHRQ LFGESEGKGG KSLFPTFSLF 

       310        320        330        340        350        360 
TTDLHSMGQL YQEGEKNFFE TVIQVQTQFH DLELPPSDFN NDDQLDYLLA KSMNEISNTA 

       370        380        390        400        410        420 
LEAVVEAHFQ SNVNIIKLTL KERTTFMFGY FYFWLSMATM MSGSLLGHNV FDQPGVEVYK 

       430 
QLMFAKLGRE 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96230.1.
PIRS73908.
RefSeqNP_109938.1. NC_000912.1.

3D structure databases

ProteinModelPortalP78033.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272634.MPN250.

Proteomic databases

PaxDbP78033.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96230; AAB96230; MPN_250.
GeneID876909.
KEGGmpn:MPN250.
PATRIC20021825. VBIMycPne110_0269.

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMAAIAFREF.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-544.
MPNE272634:GJ6Z-257-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYCPN
AccessionPrimary (citable) accession number: P78033
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names