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P78033

- G6PI_MYCPN

UniProt

P78033 - G6PI_MYCPN

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei284 – 2841Proton donorBy similarity
Active sitei305 – 3051By similarity
Active sitei420 – 4201By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-544.
MPNE272634:GJ6Z-257-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MPN_250
ORF Names:MP582
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 430430Glucose-6-phosphate isomerasePRO_0000180686Add
BLAST

Proteomic databases

PaxDbiP78033.

Interactioni

Protein-protein interaction databases

STRINGi272634.MPN250.

Structurei

3D structure databases

ProteinModelPortaliP78033.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiAIAFREF.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P78033-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESKWLTVDT KHLYGFDEAI FIQKYQKKVN QIHQQFLNQQ LPDGHMNGWY
60 70 80 90 100
SQPDQDHKGL LKQINTIAKQ FNALKVTDIV YLGIGGSYTG IRAILDFLKP
110 120 130 140 150
EQKANIKVHF VPDISAFNIA AVARAIKGKS WALVVTSKSG RTLEPAVTFR
160 170 180 190 200
YFRNLLHKQY KQKHALRTVV ITDAVKGLLV GMSNQYGYAH LTIPSNIGGR
210 220 230 240 250
FSTLSPAGLL LAKLCGHDPK QLLLGTLTAK QELANSDLNT NSAYYYAALR
260 270 280 290 300
HWLYTTKKLK IEVTVAYHSA YEYLLLQHRQ LFGESEGKGG KSLFPTFSLF
310 320 330 340 350
TTDLHSMGQL YQEGEKNFFE TVIQVQTQFH DLELPPSDFN NDDQLDYLLA
360 370 380 390 400
KSMNEISNTA LEAVVEAHFQ SNVNIIKLTL KERTTFMFGY FYFWLSMATM
410 420 430
MSGSLLGHNV FDQPGVEVYK QLMFAKLGRE
Length:430
Mass (Da):48,834
Last modified:February 1, 1997 - v1
Checksum:iBBF48166F3DCBA70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96230.1.
PIRiS73908.
RefSeqiNP_109938.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96230; AAB96230; MPN_250.
GeneIDi876909.
KEGGimpn:MPN250.
PATRICi20021825. VBIMycPne110_0269.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96230.1 .
PIRi S73908.
RefSeqi NP_109938.1. NC_000912.1.

3D structure databases

ProteinModelPortali P78033.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272634.MPN250.

Proteomic databases

PaxDbi P78033.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB96230 ; AAB96230 ; MPN_250 .
GeneIDi 876909.
KEGGi mpn:MPN250.
PATRICi 20021825. VBIMycPne110_0269.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi AIAFREF.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci MetaCyc:MONOMER-544.
MPNE272634:GJ6Z-257-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiG6PI_MYCPN
AccessioniPrimary (citable) accession number: P78033
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3