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P78013

- RPOB_MYCPN

UniProt

P78013 - RPOB_MYCPN

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Protein

DNA-directed RNA polymerase subunit beta

Gene
rpoB, MPN_516, MP326
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
  3. ribonucleoside binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-557-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit beta (EC:2.7.7.6)
Short name:
RNAP subunit beta
Alternative name(s):
RNA polymerase subunit beta
Transcriptase subunit beta
Gene namesi
Name:rpoB
Ordered Locus Names:MPN_516
ORF Names:MP326
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13911391DNA-directed RNA polymerase subunit betaUniRule annotationPRO_0000047922Add
BLAST

Proteomic databases

PaxDbiP78013.

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Protein-protein interaction databases

IntActiP78013. 14 interactions.
STRINGi272634.MPN516.

Structurei

3D structure databases

ProteinModelPortaliP78013.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0085.
KOiK03043.
OMAiENDDSAR.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 3 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P78013-1 [UniParc]FASTAAdd to Basket

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MSQKPSFFQK KYSPTATRRY YGKIATDFVQ PNLADIQIRS YQTFLDHDLE     50
NLIAAYFPIK SPNDRYTINF KGLRRTAPER NEAQSRSESK TYEIGIYADL 100
ELIDSATGTI KKPRKSKKNS ATSSVDGVFL TNLPLITRDG VFIVNGIEKF 150
VIAQITRSPG IYMLTKSQLK LSSSRKRVQE GYVCEVLPAN GSVMLIYISN 200
KKKIEDAFVQ ILLRDAVREG AKIFPITTLL KAFGMSGKEI LKVFKNNEFI 250
TRSLEAEVYN AKDFLNNVDP EIKNLLREFR DGKTDLRRKG IASDQKIRSL 300
VSDYVLLEKE HKALSEAKPN DPKVGQLEAD MDELMDKIIT ERAAKHIVHE 350
LSISLRGLEN TDECPENSYH ALLCSRFFRQ RRYNLSAAGR YKVSRKLRIT 400
ERIYQKTLAC DLHLKNGELL LKKGTLLVKE EIDKIKQAAQ NNQIDFVQKI 450
KLTTDGSAVN LSPESLLYES LDVYVNNDNF DVSVPVVGIH NDNDLNKAIT 500
LSDFIASISY VINIPSAIGK YDDIDHLGNK RVKLINELIS SRLESGITRM 550
ERFLKEKLTI ADGVNRGQQI NEEGQVIEQA EKKELTIKSL INSKPIQIVI 600
RDFFNTHQLT QFLDHQNPLS ELSNKRRISA MGPGGISRED PNLDIRDVHY 650
SQYGRICPIE TPEGMNIGLI MSLASFAKID ENGFLMAPYR KIKNGVITDE 700
VEYLTALRED EHIIAEISSL VNIDENNKIL DKEIIGRYRS MQGLYDPSKI 750
DYIDVAPHQV VSIGSSLIPF LENDDSARAL MGTNMQRQAY PLIKPYAPVV 800
GTGQEYKIAR DSGLTMLAPC SGTVKYVDNS KITIESDSGE QHTLDLIKFE 850
RSNQNTCYNH VPLVEKGQRV TKDEVIADGP AVNKSELSLG QNVLVAFTTW 900
NGYNYEDAIV ISERLVKDDV LTSLTINEYV AQCLSTKNGD EQITRDIPNV 950
SDANKRYLDE NGIIMVGAEV KEGDVLVGKV SPKGQVEVSP EEKLFKAIFP 1000
ESVQNVRDSS LKLPHGGDGI VSCVKRFSIA NGNELNDGVI EMIKVYVVQK 1050
RKIQIGDKLA GRHGNKGVIS KVVPVADMPH LEDGTPVDIL LNPLGVPSRM 1100
NIGQIFEMHL GYAAHNLAKR MLISACFDDK KAQALSTEIN QPQYKLDRLI 1150
TGLKAQITNR GLKDEQAALA QLNNGDIALV LKEIGMSFDD LHFKVATPIF 1200
QGVNFQDLQD IMDEAGLKPA ETHGKFKLID GRTGLPFEKP ISLGIMYIMK 1250
LNHMVDDKIH ARAVGPYSKI TQQPLGGKSQ NGGQRFGEME VWALEAYGAA 1300
YNLQELLTIK SDDVQGRNKA YAAIVKGAAF PEPGIPESFK LLTKELQGLA 1350
LSVSFIYDDN TQQDSNNVSI LQADGEQDDL FNDFEFDTEG Y 1391
Length:1,391
Mass (Da):155,622
Last modified:February 1, 1997 - v1
Checksum:iB2F345AB24F18EAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95974.1.
PIRiS73652.
RefSeqiNP_110204.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95974; AAB95974; MPN_516.
GeneIDi876806.
KEGGimpn:MPN516.
PATRICi20022486. VBIMycPne110_0570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95974.1 .
PIRi S73652.
RefSeqi NP_110204.1. NC_000912.1.

3D structure databases

ProteinModelPortali P78013.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P78013. 14 interactions.
STRINGi 272634.MPN516.

Proteomic databases

PaxDbi P78013.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB95974 ; AAB95974 ; MPN_516 .
GeneIDi 876806.
KEGGi mpn:MPN516.
PATRICi 20022486. VBIMycPne110_0570.

Phylogenomic databases

eggNOGi COG0085.
KOi K03043.
OMAi ENDDSAR.
OrthoDBi EOG6M9DS6.

Enzyme and pathway databases

BioCyci MPNE272634:GJ6Z-557-MONOMER.

Family and domain databases

Gene3Di 2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 3 hits.
HAMAPi MF_01321. RNApol_bact_RpoB.
InterProi IPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view ]
PANTHERi PTHR20856. PTHR20856. 1 hit.
Pfami PF04563. RNA_pol_Rpb2_1. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02013. rpoB. 1 hit.
PROSITEi PS01166. RNA_POL_BETA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiRPOB_MYCPN
AccessioniPrimary (citable) accession number: P78013
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi