P78005 (Y009_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized deoxyribonuclease MG009 homolog
EC=3.1.21.-

Gene names

Ordered Locus Names:	MPN_009
ORF Names:	D12_orf261, MP145

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129)

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Putative deoxyribonuclease By similarity.
Cofactor	Binds 2 divalent metal cations per subunit By similarity.
Sequence similarities	Belongs to the TatD DNase family.

Ontologies

Keywords
Ligand	Metal-binding
Molecular function	Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	endodeoxyribonuclease activity, producing 5'-phosphomonoesters Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 261	261	Uncharacterized deoxyribonuclease MG009 homolog		PRO_0000202007
Sites
	Metal binding	7	1	Divalent metal cation 1 By similarity
	Metal binding	9	1	Divalent metal cation 1 By similarity
	Metal binding	96	1	Divalent metal cation 1 By similarity
	Metal binding	96	1	Divalent metal cation 2 By similarity
	Metal binding	132	1	Divalent metal cation 2 By similarity
	Metal binding	156	1	Divalent metal cation 2 By similarity
	Metal binding	211	1	Divalent metal cation 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	P78005 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: D2F2EA805864C3EB	FASTA	261	29,820
	10 20 30 40 50 60 MEYFDAHCHL NCEPLLEQHE KSLANFRLIG LKANVVGTNL TNSQIAVNLA KQHPDLLKAG 70 80 90 100 110 120 VGIHPNDVQL FDLKAAQATL KKLVSTHRSF ISCIGEYGFD YHYTKDYITQ QEQFFLMQFQ 130 140 150 160 170 180 LAEQYQLVHM LHVRDVHERI YEVLKRLKPK QPVVFHCFSE DTNTALKLLT LREVGLKVYF 190 200 210 220 230 240 SIPGIVTFKN AKNLQAALSV IPTELLLSET DSPYLAPVPF RGKTNWPECV VHTVQTIADI 250 260 KQVPLAEIKQ AIVHNAKKLF W

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95793.1.
PIR	S73471.
RefSeq	NP_109697.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P78005.
ModBase	Search...
Protein-protein interaction databases
IntAct	P78005. 5 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	877360.
GenomeReviews	Gene locus MPN_009 in contig U00089_GR.
KEGG	mpn:MPN009.
PATRIC	20021291. VBIMycPne110_0009.
Phylogenomic databases
HOGENOM	HBG629833.
OMA	HPNEAPR.
PhylomeDB	P78005.
ProtClustDB	CLSK542093.
Enzyme and pathway databases
BioCyc	MPNE272634:MPN009-MONOMER.
Family and domain databases
InterPro	IPR012278. DNase_TatD. IPR018228. DNase_TatD-rel_CS. IPR015991. DNase_TatD_bac-type. IPR001130. TatD_superfamily. [Graphical view]
KO	K03424.
PANTHER	PTHR10060. TatD_DNase. 1 hit.
Pfam	PF01026. TatD_DNase. 1 hit. [Graphical view]
PIRSF	PIRSF005902. DNase_TatD. 1 hit.
TIGRFAMs	TIGR00010. TIGR00010. 1 hit.
PROSITE	PS01137. TATD_1. 1 hit. PS01090. TATD_2. False negative. PS01091. TATD_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y009_MYCPN

Accession

Primary (citable) accession number: P78005

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program