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Protein

RNA polymerase sigma factor

Gene

sigA

Organism
Thermoanaerobacterium thermosulfurigenes (Clostridium thermosulfurogenes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Name:sigAImported
OrganismiThermoanaerobacterium thermosulfurigenes (Clostridium thermosulfurogenes)Imported
Taxonomic identifieri33950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisThermoanaerobacterium

Structurei

3D structure databases

ProteinModelPortaliP77996.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 65RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini220 – 246RNA_pol_sigma70InterPro annotationAdd BLAST27

Sequence similaritiesi

Belongs to the sigma-70 factor family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiView protein in InterPro
IPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
PIRSFiPIRSF000770. RNA_pol_sigma-SigE/K. 1 hit.
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02937. sigma70-ECF. 1 hit.
PROSITEiView protein in PROSITE
PS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P77996-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKLLTKEEE KILFERLRNG DESAKDVLVE CNIRLVDKVA AGFLKSGVEF
60 70 80 90 100
DDLVQEGLIG LLTAIDKFDH TKGYKFSTYA TWYIQQSMRR YIGNYGKIIR
110 120 130 140 150
LPIHINEKIN RILKARYLIE QKKGSLATTE EISRLTGYTE EEIEGYLSYA
160 170 180 190 200
TDVISLNQYV NDERVDAELI NFIQDDTIDV EEMAIEKEIK KEIRKILDSL
210 220 230 240 250
PERERMILKM RFGFGCNLKT LTEIGNIFGL TRERIRQIQN NTIKELRHNR
260
KVKDRLREIM R
Length:261
Mass (Da):30,627
Last modified:February 1, 1997 - v1
Checksum:iA99F6038F2842242
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50951 Genomic DNA. Translation: AAB08043.1.
PIRiS72639.

Similar proteinsi

Entry informationi

Entry nameiP77996_THETU
AccessioniPrimary (citable) accession number: P77996
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: September 27, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)